| Type | Description |
|---|---|
| Definition | structural maintenance of chromosomes 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:33:00 | SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. | 33200984 |
| 2020-05-16 12:36:00 | SMC5/6 complex is essential only when meiotic DNA processing events are perturbed during mouse spermatogenesis | 30281394 |
| 2017-09-16 13:06:00 | age-dependent depletion of the SMC5/6 complex in oocytes could contribute to increased incidence of oocyte aneuploidy and spontaneous abortion in aging females. | 28302748 |
| 2014-03-01 12:15:00 | Smc6 has a role in the prevention of aberrant recombination events between pericentromeric regions during the first meiotic prophase. | 23907463 |
| 2013-10-26 10:59:00 | Mice deleted for the SMC6 gene are inviable, and mice mutated at Ser-994 in the SMC6 ATPase domain have a mild phenotype. | 23518413 |
| Type | IDs |
|---|---|
| Synonymous | 2810489L22Rik, 3830418C19Rik, AA990493, AU018782, AW742439, SMC-6, Smc6l1, mKIAA4103 |
| Gene |
UniProtKB-ID:
SMC6_MOUSE
UniprotKB:
Q924W5
UniParc:
UPI000005FB8A,
UPI0000029081
EMBL:
AK220488,
BC048790,
AJ310552,
AK014442,
AK012626,
BC026429,
AK088002,
AK148478,
AK050341,
AK011982,
AK135873,
AK009009,
AK003872,
BC090630,
BC099955
Ensembl:
ENSMUSG00000020608
KO:
mmu:67241
|
| Nucleutide sequences |
EMBL-CDS:
BAE28576.1,
BAC34200.2,
AAH26429.1,
BAE22709.1,
AAH90630.1,
BAB28365.1,
AAH99955.1,
BAC40087.2,
BAB29353.2,
CAC39250.1,
AAH48790.1,
BAD90287.1,
BAB27956.1,
BAB26022.3,
BAB23051.1
Ensembl_TRS:
ENSMUST00000218866,
ENSMUST00000020931
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020931,
ENSMUSP00000151976
RefSeq:
XP_006515236.1,
NP_001348181.1,
XP_011242194.1,
NP_001311405.1,
NP_079971.2
|
| Others |
UniRef100:
UniRef100_Q924W5
UniRef90:
UniRef90_Q924W5
UniRef50:
UniRef50_Q924W5
UniGene:
Mm.173953
CCDS:
CCDS25815.1,
CCDS88313.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员