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6722 SRF

6722

SRF

serum response factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition serum response factor

研究结论

Date Results Publications
2021-01-16 15:56:00 SRF Fusions Other Than With RELA Expand the Molecular Definition of SRF-fused Perivascular Tumors. 33021523
2020-10-24 14:05:00 Nuclear actin regulates cell proliferation and migration via inhibition of SRF and TEAD. 32119877
2020-08-01 12:53:00 SRF-FOXO1 and SRF-NCOA1 gene fusion occurs in a subset of well differentiated rhabdomyosarcoma of the neck muscles. 32187044
2020-08-01 10:54:00 Data show that transcription factor 21 (TCF21) directly interferes with formation and function of the myocardin (MYOCD)-serum response factor (SRF) complex. 31815603
2020-07-18 11:22:00 A dual luciferase reporter assay showed that both SRF mutants (G274D and G294C) impaired SRF transcriptional activity at the SRF promoter and atrial natriuretic factor (ANF) promoter (p < 0.05), additionally, the mutants displayed reduced synergism with GATA4. These results suggest that SRF-p.G274D and SRF-p.G294C may have potential pathogenic effects. 32380971

名称对应

Type IDs
Synonymous MCM1
Gene
UniProtKB-ID: SRF_HUMAN, B4DU24_HUMAN, A0A024RD16_HUMAN
UniprotKB: P11831, B4DU24, A0A024RD16
UniParc: UPI0000135F3B, UPI00017A7CD3
EMBL: BC052572, AL355385, AL133375, AK300467, CH471081, J03161, BC048211
Ensembl: ENSG00000112658
KO: hsa:6722
Nucleutide sequences
EMBL-CDS: AAA36647.1, EAX04161.1, AAH48211.1, AAH52572.1, BAG62186.1, EAX04162.1
Gene_ORFName: hCG_17638
Ensembl_TRS: ENST00000265354
Protein sequencees
Ensembl_PRO: ENSP00000265354
RefSeq: NP_003122.1, NP_001278930.1
Others
UniRef100: UniRef100_P11831, UniRef100_B4DU24
UniRef90: UniRef90_P11831, UniRef90_G3WHM2
UniRef50: UniRef50_G3WHM2, UniRef50_Q9JM73
UniGene: Hs.520140
CCDS: CCDS4889.1

全选

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