| Type | Description |
|---|---|
| Definition | sterol regulatory element binding transcription factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:26:00 | The miR-28-5p Targetome Discovery Identified SREBF2 as One of the Mediators of the miR-28-5p Tumor Suppressor Activity in Prostate | 32028704 |
| 2021-01-09 13:33:00 | Identification of a degradation signal at the carboxy terminus of SREBP2: A new role for this domain in cholesterol homeostasis. | 33106423 |
| 2020-12-12 13:25:00 | Ring finger protein 5 activates sterol regulatory element-binding protein 2 (SREBP2) to promote cholesterol biosynthesis via inducing polyubiquitination of SREBP chaperone SCAP. | 32054686 |
| 2020-09-26 13:04:00 | Selective Ah receptor modulators attenuate NPC1L1-mediated cholesterol uptake through repression of SREBP-2 transcriptional activity. | 31417158 |
| 2020-09-19 16:28:00 | COVID-19-activated SREBP2 disturbs cholesterol biosynthesis and leads to cytokine storm. | 32883951 |
| Type | IDs |
|---|---|
| Synonymous | SREBP-2, SREBP2, bHLHd2 |
| Gene |
UniProtKB-ID:
SRBP2_HUMAN,
A0A024R1Q0_HUMAN
UniprotKB:
Q12772,
A0A024R1Q0
UniParc:
UPI0000D4AC24,
UPI00001678D0
EMBL:
CT841522,
AL021453,
BC051385,
BC051799,
CH471095,
Z99716,
U02031,
BC056158
Ensembl:
ENSG00000198911
KO:
hsa:6721
|
| Nucleutide sequences |
EMBL-CDS:
AAA50746.1,
CAJ86452.1,
AAH51385.1,
AAH56158.1,
AAH51799.1,
EAW60471.1,
EAW60469.1
Gene_ORFName:
hCG_41541
Ensembl_TRS:
ENST00000361204
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354476
RefSeq:
XP_016884411.1,
XP_011528649.1,
NP_004590.2,
XP_006724373.1,
XP_016884410.1
|
| Others |
UniRef100:
UniRef100_Q12772
UniRef90:
UniRef90_Q12772
UniRef50:
UniRef50_Q12772
UniGene:
Hs.443258
CCDS:
CCDS14023.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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