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6717 SRI

6717

SRI

sorcin

protein-coding

Homo sapiens

基因描述

Type Description
Definition sorcin

研究结论

Date Results Publications
2020-12-26 13:11:00 Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome. 32305337
2019-02-09 10:46:00 REVIEW: the relationship of Sorcin with tumors as well as its regulatory mechanisms; Sorcin is increasingly considered as a potential molecular target for therapeutic intervention 30144438
2018-04-07 11:51:00 Sorcin is able to limit the toxic effects of the chemotherapeutic agent in the cell. In addition, Sorcin silencing increases cell death upon treatment with doxorubicin, increases the accumulation of doxorubicin in cell nucleus, decreases the expression of MDR1 and doxorubicin efflux via MDR1. 28726784
2017-01-28 10:59:00 Sorcin overexpression in HCT116 cells resulted in a significant increase in cell migration and invasion. Sorcin stimulated epithelial-mesenchymal transition through activating PI3K/Akt signaling. 25567655
2016-07-30 11:41:00 The authors verified that NS5A of hepatitis C virus interacted with sorcin through domain I of NS5A, and phosphorylation of the threonine residue 155 of sorcin played a crucial role in protein interaction. 26719254

名称对应

Type IDs
Synonymous CP-22, CP22, SCN, V19
Gene
UniProtKB-ID: SORCN_HUMAN, B4DHQ6_HUMAN, C9J0K6_HUMAN
UniprotKB: P30626, B4DHQ6, C9J0K6
UniParc: UPI0001B791D9, UPI00017A7408, UPI00002263A8, UPI00017A733B, UPI0000112055
EMBL: BM739144, L12387, AK295225, AK296601, AC003991, M32886, CH471091, BC011025, AC005075
Ensembl: ENSG00000075142
KO: hsa:6717
Nucleutide sequences
EMBL-CDS: EAW76910.1, BAG59214.1, AAA92155.1, AAH11025.1, AAA60588.1, EAW76909.1, BAG58218.1
Ensembl_TRS: ENST00000431660, ENST00000394641, ENST00000265729, ENST00000419179, ENST00000490437
Protein sequencees
Ensembl_PRO: ENSP00000391148, ENSP00000265729, ENSP00000378137, ENSP00000397609, ENSP00000418512
RefSeq: NP_001243821.1, XP_011514830.1, NP_003121.1, NP_001243820.1, NP_944490.1
Others
UniRef100: UniRef100_P30626, UniRef100_B4DHQ6, UniRef100_C9J0K6
UniRef90: UniRef90_P30626, UniRef90_B4DHQ6, UniRef90_C9J0K6
UniRef50: UniRef50_P30626, UniRef50_G3X196, UniRef50_B4DHQ6
UniGene: Hs.489040
CCDS: CCDS47638.1, CCDS59063.1, CCDS5612.1

全选

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