| Type | Description |
|---|---|
| Definition | neurotrophin receptor associated death domain |
| Date | Results | Publications |
|---|---|---|
| 2017-05-20 10:16:00 | The NRADD conditional and complete knockout mouse lines generated are new and useful tools to study the physiological roles of NRADD. | 27775873 |
| 2015-10-03 10:17:00 | Its reduction ameliorates cognitive deficits in Alzheimer disease. | 25443284 |
| 2015-04-11 12:32:00 | These results suggest a mechanism involving both the transmembrane domain and the death domain of p45 to regulate p75-mediated signaling. | 25093680 |
| 2014-03-08 10:57:00 | p45 forms a complex with FADD and diminishes Fas-FADD mediated death signaling. | 23935974 |
| 2011-03-11 18:25:00 | The authors show that the mammalian p75NTR homologue NRH2 critically regulates the expression of sortilin on the neuronal cell surface and promotes p75NTR and sortilin receptor complex formation, rendering cells responsive to proneurotrophins. | 19407813 |
| Type | IDs |
|---|---|
| Synonymous | 2610311B09Rik, BB104149, NRDD, NRH2, PLAIDD |
| Gene |
UniProtKB-ID:
NRADD_MOUSE
UniprotKB:
Q8CJ26
UniParc:
UPI0000028111
EMBL:
AC132103,
BC069856,
AF534394,
AK160222
Ensembl:
ENSMUSG00000032491
KO:
mmu:67169
|
| Nucleutide sequences |
EMBL-CDS:
BAE35698.1,
AAN05631.1,
AAH69856.1
Ensembl_TRS:
ENSMUST00000035069
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000035069
RefSeq:
NP_080288.1
|
| Others |
UniRef100:
UniRef100_Q8CJ26
UniRef90:
UniRef90_Q8K5A9
UniRef50:
UniRef50_Q8K5A9
UniGene:
Mm.46680
CCDS:
CCDS23569.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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