| Type | Description |
|---|---|
| Definition | metadherin |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:13:00 | A novel metadherinDelta7 splice variant enhances triple negative breast cancer aggressiveness by modulating mitochondrial function via NFkB-SIRT3 axis. | 31806873 |
| 2020-06-27 12:40:00 | Investigated the therapeutic efficacy of micheliolide (MCL) on renal fibrosis in vivo and in vitro and further investigate the underlying mechanism of metadherin (Mtdh) as a target of MCL in this condition. | 30976056 |
| 2019-10-12 11:11:00 | AEG-1 has a role in regulating macrophage activation; AEG-1 is required in both tumor cells and tumor microenvironment to stimulate hepatocarcinogenesis | 30181179 |
| 2018-07-28 11:25:00 | Data show MTDH mRNA expression upregulated in cervical cancer tissues and inversely correlated with miR-433 expression. Its knockdown showed similar tumor-suppressive roles as miR-433 overexpression in regards to cervical cancer cell proliferation, invasion and apoptosis. MTDH overexpression markedly reversed the effects of miR-433 overexpression in regards to proliferation, invasion and of cervical cancer cells. | 29130111 |
| 2018-04-10 10:30:00 | Up regulation of AEG protein plays a role in the pathogenesis of NAFLD. | 28437865 |
| Type | IDs |
|---|---|
| Synonymous | 2610103J23Rik, 3D3, 3D3/Lyric, AEG-1, AV353288, D8Bwg1112e, Lyric |
| Gene |
UniProtKB-ID:
LYRIC_MOUSE
UniprotKB:
Q80WJ7
UniParc:
UPI0000191F1A
EMBL:
BC138858,
AK151269,
AK011808,
AK151810,
AK029915,
AK035302,
BC036994,
AY553638,
AF501309,
BC023115,
BC138859
Ensembl:
ENSMUSG00000022255
KO:
mmu:67154
|
| Nucleutide sequences |
EMBL-CDS:
BAC26673.1,
AAS68097.1,
AAI38859.1,
AAH36994.1,
BAC29022.1,
AAH23115.1,
AAP30790.1,
AAI38860.1,
BAE30256.1,
BAB27854.1,
BAE30709.1
Ensembl_TRS:
ENSMUST00000022865
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022865
RefSeq:
NP_001344855.1,
XP_006520212.1,
XP_006520215.1,
XP_017172219.1,
XP_017172220.1,
XP_017172218.1,
XP_036015441.1,
NP_080278.3,
XP_006520214.1,
NP_001344854.1,
XP_017172217.1,
XP_030104570.1
|
| Others |
UniRef100:
UniRef100_Q80WJ7
UniRef90:
UniRef90_Q80WJ7
UniRef50:
UniRef50_Q86UE4
UniGene:
Mm.130883
CCDS:
CCDS27415.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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