| Type | Description |
|---|---|
| Definition | ribonuclease H2, subunit B |
| Date | Results | Publications |
|---|---|---|
| 2019-02-02 10:29:00 | Ribonuclease H2 subunit B gene functions as a colorectal tumor suppressor. | 30273559 |
| 2016-09-10 11:17:00 | Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response | 26903602 |
| 2014-06-07 12:53:00 | Recent evidence gathered from ribonuclease H2 knock-out mice provides insight into the molecular mechanisms underlying Aicardi-Goutieres syndrome development and a potential role of DNA damage as a trigger of autoimmunity is discussed. [review] | 23744109 |
| 2012-11-24 10:38:00 | Study performed targeted mutagenesis of the mouse Rnaseh2b gene to gain insight into the in vivo role of the mammalian RNase H2 enzyme. Ablation of Rnaseh2b in mice leads to early embryonic lethality due to elevated DNA damage and reduced cellular proliferation during gastrulation. | 22579044 |
| 2010-04-12 12:17:00 | Data show that the interwoven architecture of RNase H2B and RNase H2C that interface with RNase H2A in a complex ideally suited for nucleic acid binding and hydrolysis coupled to protein-protein interaction motifs. | 19923215 |
| Type | IDs |
|---|---|
| Synonymous | 1110019N06Rik, 2610207P08Rik, Dleu8 |
| Gene |
UniProtKB-ID:
RNH2B_MOUSE
UniprotKB:
Q80ZV0
UniParc:
UPI0000021D6E
EMBL:
BC047997,
AK011914,
AK082752
Ensembl:
ENSMUSG00000021932
KO:
mmu:67153
|
| Nucleutide sequences |
EMBL-CDS:
BAB27913.1,
AAH47997.1,
BAC38602.1
Ensembl_TRS:
ENSMUST00000022499
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022499
RefSeq:
NP_080277.1
|
| Others |
UniRef100:
UniRef100_Q80ZV0
UniRef90:
UniRef90_Q80ZV0
UniRef50:
UniRef50_Q5TBB1
UniGene:
Mm.26040
CCDS:
CCDS27189.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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