| Type | Description |
|---|---|
| Definition | steroid 5 alpha-reductase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:32:00 | Expression in Escherichia Coli, Purification, and Functional Reconstitution of Human Steroid 5alpha-Reductases. | 32716491 |
| 2020-09-19 16:30:00 | Associations of SRD5A1 gene variants and testosterone with dysglycemia: Henan Rural Cohort study. | 31870594 |
| 2019-12-14 12:36:00 | Deficiency or inhibition of 5alphaR1 predisposes men and mice to insulin resistance and fatty liver. | 31199473 |
| 2018-04-21 11:25:00 | The study described in this article shows that selected SRD5A1 and SRD5A2 polymorphisms can alter the levels of metabolic and hormonal parameters in patients with BPH. Special attention should be paid to the SDR5A2 rs12470143 polymorphism, which is associated with a change in lipid profile, as well as with the inheritance and incidence rate of MetS among these patients. | 29084161 |
| 2017-12-16 12:31:00 | Findings suggest that 5alpha-reductases (5-AR) isoenzymes could be explored as a therapeutic target for urothelial bladder cancer (UBC) with 5alpha-reductase inhibitors (5-ARI). | 29187470 |
| Type | IDs |
|---|---|
| Synonymous | S5AR 1 |
| Gene |
UniProtKB-ID:
S5A1_HUMAN,
B7Z4D8_HUMAN
UniprotKB:
P18405,
B7Z4D8
UniParc:
UPI00000534C8,
UPI0001914DE1
EMBL:
AF073303,
AK297208,
M68885,
M32313,
BC007033,
AF073302,
CH471102,
M68886,
M68883,
AF073301,
M68882,
AY341029,
BT006834,
M68884,
AF052126,
AK313070,
AF113128,
BC008673,
AF073304
Ensembl:
ENSG00000145545
KO:
hsa:6715
|
| Nucleutide sequences |
EMBL-CDS:
AAF14869.1,
BAG35898.1,
AAP35480.1,
AAA35490.1,
EAX08104.1,
AAA60995.1,
AAH08673.1,
AAC26863.1,
AAC28620.1,
AAH07033.1,
AAC26865.1,
AAP88935.1,
AAC26864.1,
AAC26862.1,
BAH12524.1
Ensembl_TRS:
ENST00000274192
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000274192
RefSeq:
NP_001038.1,
NP_001311252.1,
NP_001311251.1
|
| Others |
UniRef100:
UniRef100_P18405,
UniRef100_B7Z4D8
UniRef90:
UniRef90_P18405,
UniRef90_B7Z4D8
UniRef50:
UniRef50_P24008,
UniRef50_B7Z4D8
UniGene:
Hs.552
CCDS:
CCDS3870.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员