| Type | Description |
|---|---|
| Definition | hect domain and RLD 6 |
| Date | Results | Publications |
|---|---|---|
| 2016-02-06 10:55:00 | These results suggest that in addition to promoting protein ISGylation, Herc6 has a novel and protein ISGylation-independent function in the male reproductive system. | 25406959 |
| 2012-06-16 10:41:00 | Data show that the HerC6 N-terminal RCC1-like domain (RLD) allows ISG15 conjugation. | 22272257 |
| 2012-03-24 10:30:00 | mHERC6 is essential for endogenous murine ISGylation and thus represents the dominant ISG15 E3 ligase in mice. | 22138649 |
| 2010-07-26 11:50:00 | Expression of the Herc5-mediated ubiquitin-like protein ISGylation system can distinctly potentiate interferon-beta-induced antiviral effects against influenza A virus. | 20385878 |
| Type | IDs |
|---|---|
| Synonymous | 1700121D12Rik, 2510038N07Rik, 4930427L17Rik, AI451296, CEB1, Herc5 |
| Gene |
UniProtKB-ID:
HERC6_MOUSE
UniprotKB:
F2Z461
UniParc:
UPI00001E3DD4
EMBL:
AC127307,
AC142212,
AK017888,
AK149648
Ensembl:
ENSMUSG00000029798
KO:
mmu:67138
|
| Nucleutide sequences |
EMBL-CDS:
BAE29004.1,
BAB30989.3
Ensembl_TRS:
ENSMUST00000031817
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000031817
RefSeq:
NP_080268.1
|
| Others |
UniRef100:
UniRef100_F2Z461
UniRef90:
UniRef90_F2Z461
UniRef50:
UniRef50_Q8IVU3
UniGene:
Mm.297393
CCDS:
CCDS51796.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30733279 |
Development Toru Suzuki , Chisato Kikuguchi , Saori Nishijima , Takeshi Nagashima , Akinori Takahashi , Mariko Okada , Tadashi Yamamoto |
2019-02-15 | - |
| 27626380 |
High-throughput discovery of novel developmental phenotypes. Nature Mary E Dickinson , Ann M Flenniken , Xiao Ji , Lydia Teboul , Michael D Wong , Jacqueline K White , Terrence F Meehan , Wolfgang J Weninger , Henrik Westerberg , Hibret Adissu , Candice N Baker , Lynette Bower , James M Brown , L Brianna Caddle , Francesco Chiani , Dave Clary , James Cleak , Mark J Daly , James M Denegre , Brendan Doe , Mary E Dolan , Sarah M Edie , Helmut Fuchs , Valerie Gailus-Durner , Antonella Galli , Alessia Gambadoro , Juan Gallegos , Shiying Guo , Neil R Horner , Chih-Wei Hsu , Sara J Johnson , Sowmya Kalaga , Lance C Keith , Louise Lanoue , Thomas N Lawson , Monkol Lek , Manuel Mark , Susan Marschall , Jeremy Mason , Melissa L McElwee , Susan Newbigging , Lauryl M J Nutter , Kevin A Peterson , Ramiro Ramirez-Solis , Douglas J Rowland , Edward Ryder , Kaitlin E Samocha , John R Seavitt , Mohammed Selloum , Zsombor Szoke-Kovacs , Masaru Tamura , Amanda G Trainor , Ilinca Tudose , Shigeharu Wakana , Jonathan Warren , Olivia Wendling , David B West , Leeyean Wong , Atsushi Yoshiki , International Mouse Phenotyping Consortium , Jackson Laboratory , Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS) , Charles River Laboratories , MRC Harwell , Toronto Centre for Phenogenomics , Wellcome Trust Sanger Institute , RIKEN BioResource Center , Daniel G MacArthur , Glauco P Tocchini-Valentini , Xiang Gao , Paul Flicek , Allan Bradley , William C Skarnes , Monica J Justice , Helen E Parkinson , Mark Moore , Sara Wells , Robert E Braun , Karen L Svenson , Martin Hrabe de Angelis , Yann Herault , Tim Mohun , Ann-Marie Mallon , R Mark Henkelman , Steve D M Brown , David J Adams , K C Kent Lloyd , Colin McKerlie , Arthur L Beaudet , Maja BuÄan , Stephen A Murray |
2016-09-22 | - |
| 25406959 |
J. Interferon Cytokine Res. Kei-ichiro Arimoto , Takayuki Hishiki , Hiroshi Kiyonari , Takaya Abe , Chuyi Cheng , Ming Yan , Jun-Bao Fan , Mitsuru Futakuchi , Hiroyuki Tsuda , Yoshiki Murakami , Hideyuki Suzuki , Dong-Er Zhang , Kunitada Shimotohno |
2015-05-01 |
Herc6
|
| 25312643 |
Mice without macroH2A histone variants. Mol. Cell. Biol. John R Pehrson , Lakshmi N Changolkar , Carl Costanzi , N Adrian Leu |
2014-12-01 |
H2afy,
H2afy2
|
| 24029230 |
Cancer Cell Akiko Nagamachi , Hirotaka Matsui , Hiroya Asou , Yuko Ozaki , Daisuke Aki , Akinori Kanai , Keiyo Takubo , Toshio Suda , Takuro Nakamura , Linda Wolff , Hiroaki Honda , Toshiya Inaba |
2013-09-09 |
Gm13242,
Papd4,
Wdr7,
Ly76,
Pld4,
Ston2,
Krt75,
Slc8a3,
Vmn1r13,
Krtap5-5,
Cebpd,
Eef2,
Muc4,
Gsr,
Ptpn6,
Hoxb3,
Itgam,
Itgb3,
Kcnab2,
Lamp1,
Vmn1r214,
Pdgfra,
Pdgfrb,
Sirpa,
Ptprc,
Ptprz1,
Rbmy,
Rest,
Sin3a,
Serpinb9f,
Samd9l,
Dhtkd1,
Mmp21,
Eea1,
Thy1,
4930474N05Rik,
Arl11,
Top2a,
Prrc2c,
Ppp4r2,
Tcaf2,
Ptprq,
Bves,
Muc19,
Dact2,
Wdr78,
Siglecg,
Rbm47,
Zbtb24,
Rab5a,
Tmem91,
Abca15,
6330408A02Rik,
Dock1,
Kcp,
Mrgprx1,
Agpat5,
Arhgef7,
Vmn2r74,
Srsf4,
Tnfrsf13b,
Smpd3,
Rrs1,
Heatr9,
Zfp784,
Slc7a6os,
Gpatch4,
Acp6,
Herc6,
Dock7,
Narfl,
4930430F08Rik,
Eml1,
Hrnr,
Anln,
Cyp2c66,
Tmem143,
3830403N18Rik,
Col24a1,
Serpinb12,
Esco2,
Pygo1,
Ssbp3,
Sipa1l3,
Wdr38,
Armc6,
Tmem190,
Apobec3,
SAMD9,
EEA1
|
| 23012479 |
Impact of lactobacilli on orally acquired listeriosis. Proc. Natl. Acad. Sci. U.S.A. Cristel Archambaud , Marie-Anne Nahori , Guillaume Soubigou , Christophe Bécavin , Laure Laval , Pierre Lechat , Tamara Smokvina , Philippe Langella , Marc Lecuit , Pascale Cossart |
2012-10-09 | - |
| 22138649 |
mHERC6 is the essential ISG15 E3 ligase in the murine system. Biochem. Biophys. Res. Commun. Lars Ketscher , Anja Basters , Marco Prinz , Klaus-Peter Knobeloch |
2012-01-06 |
Isg15,
Herc6
|
| 22272257 |
HERC6 is the main E3 ligase for global ISG15 conjugation in mouse cells. PLoS ONE Diede Oudshoorn , Sander van Boheemen , Maria Teresa Sánchez-Aparicio , Ricardo Rajsbaum , Adolfo GarcÃa-Sastre , Gijs A Versteeg |
2012-01-01 |
Isg15,
Herc6
|
| 20385878 |
Herc5 attenuates influenza A virus by catalyzing ISGylation of viral NS1 protein. J. Immunol. YuJie Tang , Gongxun Zhong , Lianhui Zhu , Xing Liu , Yufei Shan , Huapeng Feng , ZhiGao Bu , Hualan Chen , Chen Wang |
2010-05-15 |
Isg15,
Herc6
|
| 16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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