| Type | Description |
|---|---|
| Definition | spectrin beta, non-erythrocytic 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:53:00 | SPTBN1 suppresses the progression of epithelial ovarian cancer via SOCS3-mediated blockade of the signaling pathway. | 32516133 |
| 2020-04-11 12:41:00 | Data suggeset the novel mutation (c.5650G > C/p.Ala1884Pro) of beta-spectrin (SPTB) to be the genetic lesion in this family of hereditary spherocytosis (HS). | 30690801 |
| 2020-03-28 10:05:00 | beta2 spectrin induced the differentiation of liver cancer stem cells, and then repressed the CSCs properties in liver tumorinitiating cells. Transduction of beta2SP into liver CSCs resulted in a reduction in colony formation ability, spheroid formation capacity, invasive activity, chemo-resistance properties, tumorigenicity in vivo. | 29555987 |
| 2017-12-02 11:39:00 | c-Met overexpression, HER-2 gene amplification, and SPTBN1-ALK gene fusion can coexist in lung adenocarcinoma and may become a potential biomarker of cancer refractory to crizotinib, chemotherapy, and radiotherapy as well as of a relatively poor prognosis. | 27496196 |
| 2017-07-22 12:01:00 | Subjects whose head and neck tumors expressed spectrin were 4.60 times more likely (hazard ratio; 95% confidence interval: 1.88-11.25) to die at any given time when compared with those without spectrin (P = .001). | 27095047 |
| Type | IDs |
|---|---|
| Synonymous | ELF, HEL102, SPTB2, betaSpII |
| Gene |
UniProtKB-ID:
SPTB2_HUMAN,
B2ZZ89_HUMAN
UniprotKB:
Q01082,
B2ZZ89
UniParc:
UPI0000208437,
UPI0000DBEE4B,
UPI0000DBEE4C
EMBL:
AC093110,
AC092839,
AJ005694,
AF327441,
AB209748,
M96803,
AB371586,
CH471053,
AJ238723,
EU794662,
BC137283,
S65762,
BC137282
Ensembl:
ENSG00000115306
KO:
hsa:6711
|
| Nucleutide sequences |
EMBL-CDS:
BAD92985.1,
EAX00147.1,
AAB28324.1,
CAA06678.1,
AAI37284.1,
AAY24229.1,
AAI37283.1,
CAB91088.1,
AAO15362.1,
AAA60580.1,
EAX00141.1,
BAG48315.1,
ACJ13716.1,
EAX00140.1,
EAX00143.1
Gene_ORFName:
hCG_17370
Ensembl_TRS:
ENST00000356805,
ENST00000333896
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000349259,
ENSP00000334156
RefSeq:
NP_003119.2,
XP_016860269.1,
XP_016860268.1,
XP_005264574.1,
XP_005264575.1,
NP_842565.2,
XP_016860270.1,
XP_006712150.1
|
| Others |
UniRef100:
UniRef100_Q01082
UniRef90:
UniRef90_Q01082
UniRef50:
UniRef50_Q01082
UniGene:
Hs.503178,
Hs.705692
CCDS:
CCDS33199.1,
CCDS33198.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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