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67078 Pgp

67078

Pgp

phosphoglycolate phosphatase

protein-coding

Mus musculus

基因描述

Type Description
Definition phosphoglycolate phosphatase

研究结论

Date Results Publications
2018-04-28 10:44:00 Knockin replacement of Pgp with its phosphatase-inactive Pgp(D34N) mutant is embryonically lethal due to intrauterine growth arrest and developmental delay in midgestation. PGP inactivation attenuated triosephosphate isomerase activity, increased triglyceride levels at the expense of the cellular phosphatidylcholine content, and inhibited cell proliferation. 27731369
2018-01-13 10:51:00 our findings establish that PGP, an aspartate-dependent HAD phosphatase, is transiently inactivated by reversible oxidation in cells 27179418
2016-06-28 11:32:00 A previously known phosphoglycolate phosphatase (PGP) with an uncertain function acts as a specific glycerol-3-phosphate phosphatase and plays a role in the glucose and lipid metabolism and signaling, and the response to metabolic stress. 26755581
2014-04-12 12:20:00 Evolutionary and structural analyses of mammalian haloacid dehalogenase-type phosphatases AUM and chronophin provide insight into the basis of their different substrate specificities. 24338473

名称对应

Type IDs
Synonymous 1700012G19Rik, AI481330, AUM, G3PP
Gene
UniProtKB-ID: PGP_MOUSE
UniprotKB: Q8CHP8
UniParc: UPI00000E8D3F
EMBL: BC040100
Ensembl: ENSMUSG00000043445
KO: mmu:67078
Nucleutide sequences
EMBL-CDS: AAH40100.1
Ensembl_TRS: ENSMUST00000053024
Protein sequencees
Ensembl_PRO: ENSMUSP00000052866
RefSeq: NP_080230.2
Others
UniRef100: UniRef100_Q8CHP8
UniRef90: UniRef90_Q8CHP8
UniRef50: UniRef50_Q8CHP8
UniGene: Mm.28541, Mm.486259
CCDS: CCDS28482.1

全选

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研究热度

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