| Type | Description |
|---|---|
| Definition | NDC80 kinetochore complex component |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:28:00 | Prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes. | 32461611 |
| 2017-10-21 11:52:00 | These data strongly indicated that KNTC2 is a promising target for the treatment of HCC and that phosphorylated HH3 at serine 10 is one of the target engagement markers for KNTC2. | 28843857 |
| 2017-08-19 10:53:00 | Further investigation of the phosphoregulation of meiotic Kif4 revealed that Aurora Kinase and Cdk activity is critical for Kif4 kinetochore localization and interaction with Ndc80 and CENP-C. Finally, Kif4 protein but not gene expression was found to be upregulated with age, suggesting a role for this protein in the decline of oocyte quality with age | 28125646 |
| 2013-06-15 11:35:00 | Hec1-dependent cyclin B2 stabilization during early metaphase is important for early-stage spindle assembly. | 23541922 |
| 2011-09-10 12:10:00 | Disruption of Ndc80 function by either siRNA injection or antibody injection resulted in severe chromosome misalignment, spindle disruption, and precocious polar body extrusion. | 21600073 |
| Type | IDs |
|---|---|
| Synonymous | 2610020P18Rik, AV139730, HEC, HEC1, Kntc2 |
| Gene |
UniProtKB-ID:
NDC80_MOUSE
UniprotKB:
Q9D0F1
UniParc:
UPI00000E6995
EMBL:
AK169427,
BC020131,
AK011497,
AF326730,
AK163317,
AK136236
Ensembl:
ENSMUSG00000024056
KO:
mmu:67052
|
| Nucleutide sequences |
EMBL-CDS:
AAK01425.1,
BAE41169.1,
BAB27657.1,
BAE22889.1,
BAE37296.1,
AAH20131.1
Ensembl_TRS:
ENSMUST00000024851
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000024851
RefSeq:
NP_075783.2
|
| Others |
UniRef100:
UniRef100_Q9D0F1
UniRef90:
UniRef90_Q9D0F1
UniRef50:
UniRef50_Q9D0F1
UniGene:
Mm.225956
CCDS:
CCDS28959.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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