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67013 Oma1

67013

Oma1

OMA1 zinc metallopeptidase

protein-coding

Mus musculus

基因描述

Type Description
Definition OMA1 zinc metallopeptidase

研究结论

Date Results Publications
2021-04-17 13:14:00 Mitochondrial Safeguard: a stress response that offsets extreme fusion and protects respiratory function via flickering-induced Oma1 activation. 33200421
2020-02-15 12:43:00 EGCG directly interacted with OMA1 and potently inhibited self-cleavage of OMA1, leading to attenuated OPA1 cleavage. This study, therefore, suggests to use OMA1 inhibition induced by EGCG to treat cardiac hypoxia-reperfusion injury. 30518622
2017-09-02 10:21:00 The m-AAA protease associated with neurodegeneration limits MCU activity in mitochondria. 27642048
2016-08-13 11:57:00 stress-induced OMA1 activation and guanosine triphosphatase OPA1 cleavage limit mitochondrial fusion and promote neuronal death 26783299
2016-07-02 11:12:00 The IMQC protease Oma1 is required for the stability of the respiratory supercomplexes and thus balanced and tunable bioenergetic function. 26365306

名称对应

Type IDs
Synonymous 2010001O09Rik, MPRP-1, ZMPOMA1
Gene
UniProtKB-ID: OMA1_MOUSE
UniprotKB: Q9D8H7
UniParc: UPI00015B3BE0, UPI000002752F
EMBL: AL772338, AK076209, AK008020, AK136208, BC016238
Ensembl: ENSMUSG00000035069
KO: mmu:67013
Nucleutide sequences
EMBL-CDS: AAH16238.1, BAE22875.1, BAC36255.1, BAB25414.1
Ensembl_TRS: ENSMUST00000035780
Protein sequencees
Ensembl_PRO: ENSMUSP00000045269
RefSeq: XP_036020250.1, XP_006503366.1, XP_017175849.1, XP_006503362.1, XP_030109573.1, XP_036020252.1, XP_036020251.1, XP_006503365.1, XP_030109574.1, XP_006503364.1, NP_080185.1, XP_006503363.1, XP_036020249.1
Others
UniRef100: UniRef100_Q9D8H7
UniRef90: UniRef90_Q9D8H7
UniRef50: UniRef50_Q9D8H7
UniGene: Mm.30021
CCDS: CCDS18412.1

全选

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