| Type | Description |
|---|---|
| Definition | CDGSH iron sulfur domain 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 11:33:00 | Cisd2 overexpression promoted survival and alleviated the pathological defects associated with Alzheimer disease (AD). Conversely, Cisd2 deficiency accelerated AD pathogenesis. Cisd2 overexpression protected against Abeta-mediated mitochondrial damage and attenuated loss of neurons and neuronal progenitor cells. | 31837018 |
| 2020-02-29 11:34:00 | Cisd2 is essential to delaying cardiac aging and to maintaining heart functions. | 31593566 |
| 2018-08-04 10:37:00 | CISD2 haploinsufficiency disrupts calcium homeostasis, causing ER stress and subsequent nonalcoholic fatty liver disease and nonalcoholic steatohepatitis | 29166610 |
| 2017-12-09 12:11:00 | These results suggest that the thermosensitive FA-loaded hydrogel could rescue Cisd2(-/-) CM from oxidative stress-induced damage and may have potential applications in the future treatment of CVD. | 27392289 |
| 2016-11-07 14:17:00 | NAF-1, a BCL-2-associated autophagy regulator, is required for homeostatic maintenance of skeletal muscle | 22343142 |
| Type | IDs |
|---|---|
| Synonymous | 1500009M05Rik, 1500026J14Rik, 1500031D15Rik, AI848398, B630006A20Rik, Miner1, Naf-1, Noxp70, Zcd2 |
| Gene |
UniProtKB-ID:
CISD2_MOUSE
UniprotKB:
Q9CQB5
UniParc:
UPI0000022DEA
EMBL:
AM162549,
BC058279,
AK003486,
AK004257,
AK005184
Ensembl:
ENSMUSG00000028165
KO:
mmu:67006
|
| Nucleutide sequences |
EMBL-CDS:
CAJ44265.1,
BAB22814.1,
AAH58279.1,
BAB23237.1,
BAB23868.1
Ensembl_TRS:
ENSMUST00000029815
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029815
RefSeq:
NP_080178.1
|
| Others |
UniRef100:
UniRef100_Q9CQB5
UniRef90:
UniRef90_Q9CQB5
UniRef50:
UniRef50_Q9CQB5
UniGene:
Mm.269993
CCDS:
CCDS17856.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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