| Type | Description |
|---|---|
| Definition | biphenyl hydrolase like |
| Date | Results | Publications |
|---|---|---|
| 2015-06-27 12:04:00 | The catalytic efficiency (kcat/Km) of rBPHL for homocysteine thiolactone hydrolysis was 7.7 x 10(4) M(-1)s(-1), orders of magnitude higher than that of PON1 or Blmh, indicating a more significant physiological role for BPHL in detoxifying HCTL | 25333274 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20877624 |
| 2010-04-07 21:40:00 | Observational study of gene-disease association. (HuGE Navigator) | 20237496 |
| 2010-01-21 00:00:00 | BPHL catalyzes the hydrolytic activation of the antiviral prodrugs valacyclovir and valganciclovir. | 15832508 |
| 2003-06-08 16:53:00 | BPHL is a serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nuceloside analogs such as valacyclovir and valganciclovir. | 12732646 |
| Type | IDs |
|---|---|
| Synonymous | BPH-RP, MCNAA, VACVASE |
| Gene |
UniProtKB-ID:
BPHL_HUMAN,
PARG_HUMAN,
Q49AI2_HUMAN,
A0A024QZY0_HUMAN
UniprotKB:
Q86WA6,
Q86W56,
Q49AI2,
A0A024QZY0
UniParc:
UPI000000DC97,
UPI000018CEA9,
UPI000056F183,
UPI00003BECAE,
UPI00003BECAD,
UPI00029CD9A8,
UPI000000DC96,
UPI000156572D
EMBL:
AL031963,
BC106901,
AY575848,
AK302560,
EF382674,
BC050560,
AY575849,
AF005043,
AK314909,
BC037778,
BC052966,
AY258587,
AK295786,
CH471087,
AJ617684,
JQ890226,
X57653,
X81372
Ensembl:
ENSG00000227345,
ENSG00000137274
KO:
hsa:8505,
hsa:670
|
| Nucleutide sequences |
EMBL-CDS:
CAA40859.1,
CAA57137.1,
AAI06902.1,
CAE85120.1,
EAW55122.1,
AAT66421.1,
AAH50560.1,
AAP83314.1,
ABR10027.1,
AAH52966.1,
AAB61614.1,
BAG63826.1,
AAT66422.1,
BAG37421.1,
BAG58607.1,
AFM56043.1,
AAH37778.1,
EAW55119.1,
EAW55123.1
Gene_ORFName:
hCG_22877,
hCG_22877
Ensembl_TRS:
ENST00000380379,
ENST00000434640,
ENST00000380375,
ENST00000616448,
ENST00000402038,
ENST00000380368
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000390472,
ENSP00000369739,
ENSP00000369734,
ENSP00000384408,
ENSP00000484285,
ENSP00000369726
RefSeq:
NP_004323.2,
NP_001289706.1
|
| Others |
UniRef100:
UniRef100_Q86WA6,
UniRef100_Q49AI2,
UniRef100_Q86W56,
UniRef100_A0A024QZY0
UniRef90:
UniRef90_A0A2K5YUB7,
UniRef90_Q86W56,
UniRef90_A0A2R9B2K1,
UniRef90_Q86WA6
UniRef50:
UniRef50_A0A2K5YUB7,
UniRef50_Q86WA6,
UniRef50_Q86W56,
UniRef50_I3LYT0
UniGene:
Hs.10136
CCDS:
CCDS78105.1,
CCDS4483.2,
CCDS73130.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员