| Type | Description |
|---|---|
| Definition | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-10 12:39:00 | Study in HT-29 cells and mouse colorectal tumor models revealed that levels of the proteasome assembly inhibitor PSMD5/S5B are significantly decreased in tumors, and re-expression of PSMD5 blocks 26S proteasome assembly. These results suggest that intestinal cancer cells escape proteotoxic stress by reducing PSMD5 to stimulate 26S proteasome assembly. | 29716915 |
| 2013-03-02 13:17:00 | the critical role of S5b/PSMD5 in negative regulation of proteasome by TNF-alpha/NFkappaB and provide insights into proteasome inhibition in human disease. | 22921402 |
| Type | IDs |
|---|---|
| Synonymous | 1500032A03Rik, AW475925, S5b, W91691, mKIAA0072 |
| Gene |
UniProtKB-ID:
PSMD5_MOUSE
UniprotKB:
Q8BJY1
UniParc:
UPI0000022A2A
EMBL:
AK220321,
CH466542,
AL929068,
AK145587,
AK032992,
AK078419,
BC019112,
AK148284
Ensembl:
ENSMUSG00000026869
KO:
mmu:66998
|
| Nucleutide sequences |
EMBL-CDS:
BAD90393.1,
BAC37265.1,
BAE28457.1,
EDL08630.1,
BAC28117.1,
BAE26526.1
Ensembl_TRS:
ENSMUST00000028225
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028225
RefSeq:
XP_030107835.1,
XP_017174701.1,
NP_542121.2,
NP_001342473.1
|
| Others |
UniRef100:
UniRef100_Q8BJY1
UniRef90:
UniRef90_Q8BJY1
UniRef50:
UniRef50_Q8BJY1
UniGene:
Mm.270632
CCDS:
CCDS15953.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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