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66993 Smarcd3

66993

Smarcd3

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3

protein-coding

Mus musculus

基因描述

Type Description
Definition SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3

研究结论

Date Results Publications
2018-01-13 12:18:00 work revealed functional redundancy between Baf60a and Baf60c in maintaining oxidative and glycolytic metabolism in skeletal myofibers and exercise endurance. Unexpectedly, mice lacking these two factors in skeletal muscle were protected from diet-induced and age-associated metabolic disorders. Transcriptional profiling analysis identified the muscle thermogenic gene program and myokine secretion as key pathways that inte 29092888
2017-02-18 10:33:00 These data suggested that Baf60c plays an important role in cardiomyocyte proliferation in heart development and regeneration. This is the first study indicating that Baf60c contributes to the heart regeneration in vertebrates. 27125315
2016-08-20 11:29:00 postmitotic expression SOD1G93A mutant gene promotes a FAPS phenotype in C2C12 cells, by upregulating HDAC4 protein and preventing the BAF60C-SWI/SNF complex myogenic commitment 26491230
2014-06-21 11:01:00 regulates the Nodal/Bone Morphogenetic Protein antagonist Cerberus and the Baf60c/Smarcd3 subunit of the Brg1/Brm-associated factors (BAF) chromatin-remodelling complex 23787002
2014-01-04 10:48:00 Overexpression of transcription factors MYOCD and SRF alone or in conjunction with Mesp1 and SMARCD3 enhanced the basal but necessary cardio-inducing effect of the previously reported GATA4, TBX5, and MEF2C. 23704920

名称对应

Type IDs
Synonymous 1500001J14Rik, 2210409C08Rik, BAF60C
Gene
UniProtKB-ID: SMRD3_MOUSE
UniprotKB: Q6P9Z1
UniParc: UPI000049E3A3
EMBL: AK005094, BC060525, BC013122, AK019374
Ensembl: ENSMUSG00000028949
KO: mmu:66993
Nucleutide sequences
EMBL-CDS: AAH13122.2, BAB31685.2, BAB23813.1, AAH60525.1
Ensembl_TRS: ENSMUST00000030791
Protein sequencees
Ensembl_PRO: ENSMUSP00000030791
RefSeq: XP_030110630.1, XP_030110631.1, XP_006535859.2, XP_006535862.1, XP_006535861.2, XP_006535860.1, NP_080167.3, XP_030110629.1
Others
UniRef100: UniRef100_Q6P9Z1
UniRef90: UniRef90_Q6STE5
UniRef50: UniRef50_Q6STE5
UniGene: Mm.436539
CCDS: CCDS19126.1

全选

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