| Type | Description |
|---|---|
| Definition | sepiapterin reductase |
| Date | Results | Publications |
|---|---|---|
| 2017-05-20 15:04:00 | The allele frequencies for the SPR c.596-2A > G (0.7%) polymorphism is not a major cause of Parkinson's disease in the Maltese. | 27613114 |
| 2016-02-27 11:42:00 | We earlier presented evidence for a physical interaction between ODC and SPR and we showed that knockdown of SPR expression significantly reduced native ODC enzyme activity and impeded Neuroblastoma cell proliferation. | 26093909 |
| 2014-12-20 12:55:00 | new homozygous mutation in the SPR gene was found in two sisters with dopa-responsive dystonia | 24588500 |
| 2014-04-19 10:11:00 | Authors identified SPR as a novel regulator of ODC enzyme activity and, based on clinical evidence, present a model in which SPR drives ODC-mediated malignant progression in neuroblastoma. | 24096079 |
| 2013-09-14 10:42:00 | SPR-mediated reduction of sepiapterin and redox cycling occur by distinct mechanisms | 23640889 |
| Type | IDs |
|---|---|
| Synonymous | SDR38C1 |
| Gene |
UniProtKB-ID:
SPRE_HUMAN
UniprotKB:
P35270
UniParc:
UPI000004C79D
EMBL:
AK222942,
AB017547,
CH471053,
BC017310,
M76231,
AK291856,
AC092630
Ensembl:
ENSG00000116096
KO:
hsa:6697
|
| Nucleutide sequences |
EMBL-CDS:
AAY15035.1,
BAD96662.1,
BAF84545.1,
EAW99757.1,
AAA60314.1,
EAW99758.1,
BAA34534.1,
AAH17310.1
Ensembl_TRS:
ENST00000234454
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000234454
RefSeq:
NP_003115.1
|
| Others |
UniRef100:
UniRef100_P35270
UniRef90:
UniRef90_P35270
UniRef50:
UniRef50_P35270
UniGene:
Hs.301540
CCDS:
CCDS1920.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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