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66953 Cdca7

66953

Cdca7

cell division cycle associated 7

protein-coding

Mus musculus

基因描述

Type Description
Definition cell division cycle associated 7

研究结论

Date Results Publications
2020-11-21 13:31:00 The ZBTB24-CDCA7 axis regulates HELLS enrichment at centromeric satellite repeats to facilitate DNA methylation. 31970665
2019-12-14 12:04:00 The results demonstrated that the C382Y and C407G mutations in mouse ZBTB24 abolish specific DNA binding and fail to induce Cdca7 expression, modeling the events in immunodeficiency-centromeric instability-facial anomalies syndrome in humans. 31226215
2018-01-13 11:43:00 Pax6 normally represses Cdca7 expression in the lateral cortex and that repression of Cdca7 in cells of this region is required for their production of a normal complement of Tbr2-expressing intermediate progenitors 28583079
2017-07-22 12:26:00 Transcriptome analysis identified Cdca7 as the top down-regulated gene in Zbtb24 homozygous mutant mESCs, which can be restored by ectopic ZBTB24 expression. Finally, we show that this regulation is conserved between species and that CDCA7 levels are reduced in patients carrying ZBTB24 nonsense mutations 27466202

名称对应

Type IDs
Synonymous 2310021G01Rik, AU044109, JPO1
Gene
UniProtKB-ID: CDCA7_MOUSE
UniprotKB: Q9D0M2
UniParc: UPI00000299DA
EMBL: AK153943, BC066169, AK167734, AK011289, AK075882, AK028671
Ensembl: ENSMUSG00000055612
KO: mmu:66953
Nucleutide sequences
EMBL-CDS: BAC26058.1, BAE39775.1, AAH66169.1, BAC36027.1, BAB27519.1, BAE32269.1
Ensembl_TRS: ENSMUST00000102691
Protein sequencees
Ensembl_PRO: ENSMUSP00000099752
RefSeq: NP_080142.1, XP_030107833.1, XP_006500116.1
Others
UniRef100: UniRef100_Q9D0M2
UniRef90: UniRef90_Q9D0M2
UniRef50: UniRef50_Q9BWT1-2
UniGene: Mm.270676
CCDS: CCDS16121.1

全选

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研究热度

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