| Type | Description |
|---|---|
| Definition | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) |
| Date | Results | Publications |
|---|---|---|
| 2015-06-20 12:44:00 | mutation of the FpSDH target tyrosine abolishes the capacity of mitochondria to adjust metabolism upon nutrient restriction, hypoxia/reoxygenation, and T cell activation, demonstrating the physiological relevance of this adaptive response. | 24856931 |
| 2012-09-01 11:06:00 | Tumor-derived FH and SDH mutations accumulate fumarate and succinate, leading to enzymatic inhibition of multiple alpha-KG-dependent dioxygenases and consequent alterations of genome-wide histone and DNA methylation. | 22677546 |
| 2012-07-14 10:33:00 | Data show that SdhA is required for preventing AIM2 inflammasome activation. | 22474394 |
| 2012-02-18 11:07:00 | Data show that two subunits of complex II (succinate dehydrogenase, or SDH), SDHA and SDHB, interacted specifically with SIRT3. | 21858060 |
| 2011-03-05 10:43:00 | Cocaine could inhibit the activities of ATPase, LDH and SDH in cultured splenocytes. | 20653129 |
| Type | IDs |
|---|---|
| Synonymous | 1500032O14Rik, 2310034D06Rik, 4921513A11, C81073, FP, SDH2, SDHF |
| Gene |
UniProtKB-ID:
SDHA_MOUSE
UniprotKB:
Q8K2B3
UniParc:
UPI00000E88DA
EMBL:
AK034928,
AK162148,
AK169254,
BC011301,
AK147286,
AF095938,
AK145923,
DQ402975,
AK153085,
AK049590,
BC031849,
AK147624,
AK029520,
AK004362,
AK050475,
AK075990
Ensembl:
ENSMUSG00000021577
KO:
mmu:66945
|
| Nucleutide sequences |
EMBL-CDS:
BAE27822.1,
BAC33831.1,
BAC36101.1,
BAE41018.1,
BAE28032.1,
BAC34276.1,
BAE26754.1,
AAC72373.1,
BAE43173.1,
AAH11301.1,
BAC28884.1,
BAE36754.1,
AAH31849.1,
BAE31710.1,
BAC26491.1,
ABD77308.1
Ensembl_TRS:
ENSMUST00000022062
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022062
RefSeq:
NP_075770.1
|
| Others |
UniRef100:
UniRef100_Q8K2B3
UniRef90:
UniRef90_P31040
UniRef50:
UniRef50_P31040
UniGene:
Mm.158231
CCDS:
CCDS26643.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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