| Type | Description |
|---|---|
| Definition | succinate dehydrogenase complex, subunit D, integral membrane protein |
| Date | Results | Publications |
|---|---|---|
| 2018-06-09 11:21:00 | Sdhd knockout from the thyroid is sufficient to cause excess thyroid cell growth in mice, which may play a role in tumor initiation | 28928232 |
| 2017-09-23 12:30:00 | the actual dependency of undifferentiated hematopoietic stem cells on mitochondrial function, we have performed an analysis of the hematopoiesis in a mouse mutant, named SDHD-ESR, with inducible deletion of the mitochondrial protein-encoding SdhD gene, is reported. | 27929539 |
| 2016-05-21 10:18:00 | Loss of SDH activity leads to changes in the metabolism of non-essential amino acids. | 26522426 |
| 2015-01-24 10:11:00 | In mice with conditional knockout of Sdhd, we found that the Cdkn1a gene was up-regulated in kidney and adrenal. This gene encodes the cyclin-dependent kinase inhibitor p21(WAF1/Cip1), a factor implicated in cell cycle, senescence, and cancer. | 24465590 |
| 2012-10-20 10:20:00 | complete loss of SdhD is not sufficient to induce tumorigenesis in mice | 22711987 |
| Type | IDs |
|---|---|
| Synonymous | 3110001M13Rik, AVLL5809, C78570, PRO19626 |
| Gene |
UniProtKB-ID:
DHSD_MOUSE
UniprotKB:
Q9CXV1
UniParc:
UPI0000048F4F
EMBL:
BC145733,
AK135970,
AK013962,
BC145731
Ensembl:
ENSMUSG00000000171
KO:
mmu:66925
|
| Nucleutide sequences |
EMBL-CDS:
BAB29086.2,
BAE22752.1,
AAI45732.1,
AAI45734.1
Ensembl_TRS:
ENSMUST00000000175
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000000175
RefSeq:
NP_080124.1
|
| Others |
UniRef100:
UniRef100_Q9CXV1
UniRef90:
UniRef90_Q9CXV1
UniRef50:
UniRef50_O14521
UniGene:
Mm.10406
CCDS:
CCDS40623.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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