| Type | Description |
|---|---|
| Definition | serine peptidase inhibitor, Kunitz type 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:48:00 | Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction. | 32415092 |
| 2020-02-15 11:08:00 | Hypomethylation of the HAI-1 promoter contributed to the elevated HAI-1 expression in HCC tissues. In addition, the hypomethylation of the HAI-1 promoter region correlated with poor differentiation status of HCC tissues. | 31558918 |
| 2019-10-26 11:33:00 | CDX2 has a dual function in regulating both ST14 and SPINT1, gene expression in intestinal cells. We find that CDX2 is not required for the basal ST14 and SPINT1 gene expression; however changes in CDX2 expression affects the ST14/SPINT1 mRNA ratio. | 30087389 |
| 2019-03-02 11:52:00 | show that HA activation by the TMPRSS11A-related enzymes human airway tryptase and DESC1, but not TMPRSS11A itself, is blocked by the cellular serine protease inhibitor hepatocyte growth factor activator inhibitor type-1 (HAI-1). | 29976755 |
| 2018-07-28 10:54:00 | The SPINT1 expression was associated with extrathyroidal invasion, lymphovascular invasion, lymph node metastasis, advanced TNM stage, and a higher risk of recurrence in differentiated thyroid cancer. | 29532159 |
| Type | IDs |
|---|---|
| Synonymous | HAI, HAI1, MANSC2 |
| Gene |
UniProtKB-ID:
SPIT1_HUMAN
UniprotKB:
O43278
UniParc:
UPI00001AE46F,
UPI0000001058
EMBL:
BC018702,
AY358969,
BC004140,
AY296715,
BT007425,
AB000095
Ensembl:
ENSG00000166145
KO:
hsa:6692
|
| Nucleutide sequences |
EMBL-CDS:
AAH18702.1,
AAP44001.1,
AAQ89328.1,
BAA25014.1,
AAP36093.1,
AAH04140.1
Gene_ORFName:
UNQ223/PRO256
Ensembl_TRS:
ENST00000562057,
ENST00000344051
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000342098,
ENSP00000457076
RefSeq:
NP_001373803.1,
NP_001373802.1,
NP_857593.1,
NP_001373804.1,
NP_001027539.1,
NP_003701.1
|
| Others |
UniRef100:
UniRef100_O43278
UniRef90:
UniRef90_O43278
UniRef50:
UniRef50_O43278
UniGene:
Hs.233950
CCDS:
CCDS45231.1,
CCDS10067.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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