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66902 Mtap

66902

Mtap

methylthioadenosine phosphorylase

protein-coding

Mus musculus

基因描述

Type Description
Definition methylthioadenosine phosphorylase

研究结论

Date Results Publications
2017-10-14 10:50:00 Germline Mutations in Mtap is associated with lymphomagenesis. 23840755
2017-06-24 11:53:00 Data demonstrate that MTAP deficiency leads to accumulation of MTA inducing deregulation of central cellular pathways that control cell fate and contributes to the onset of a proliferative and antiapoptotic phenotype in the liver. 26819315
2014-09-13 12:14:00 MTAP-mediated regulation of methylthioadenosine links polyamine metabolism with NF-kappaB activation and apoptosis in hepatic stellate cells. 24324622
2010-01-21 00:00:00 Studies show that Mtap is a tumor suppressor gene independent of CDKN2A and ARF. 19567676
2010-01-21 00:00:00 Regulation of MTAP by reactive oxygen species might participate in the redox regulation of the methionine catabolic pathway in the liver 18237276

名称对应

Type IDs
Synonymous 1300019I21Rik, MSAP
Gene
UniProtKB-ID: MTAP_MOUSE
UniprotKB: Q9CQ65
UniParc: UPI000002992F
EMBL: AK167319, AK005064, BC003858, AK011421, AB056100
Ensembl: ENSMUSG00000062937
KO: mmu:66902
Nucleutide sequences
EMBL-CDS: BAB23788.1, BAE39421.1, BAB27609.1, AAH03858.1, BAB32865.1
Ensembl_TRS: ENSMUST00000058030
Protein sequencees
Ensembl_PRO: ENSMUSP00000061092
RefSeq: NP_077753.1
Others
UniRef100: UniRef100_Q9CQ65
UniRef90: UniRef90_Q9CQ65
UniRef50: UniRef50_Q13126
UniGene: Mm.28500
CCDS: CCDS18349.1

全选

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研究热度

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