| Type | Description |
|---|---|
| Definition | BAI1-associated protein 2-like 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-02 11:06:00 | IRTKS localizes to the distal tips of actively growing microvilli via a mechanism that requires its N-terminal I-BAR domain. At microvillar tips, IRTKS promotes elongation through a mechanism involving its C-terminal actin-binding WH2 domain. | 30197089 |
| 2018-10-20 11:37:00 | double knockout of IRSp53 and its closest family member, IRTKS, resulted in exacerbated placental abnormalities, particularly in spongiotrophoblast differentiation and development, giving rise to complete embryonic lethality. | 28067313 |
| 2017-08-05 10:12:00 | Rho family GTPases use the I-BAR proteins, IRSp53 (also known as BAIAP2), IRTKS and Pinkbar, as a central mechanism to modulate cell morphology. | 27278019 |
| 2016-08-31 17:57:00 | The IRTKS, as an adaptor of the insulin receptor (IR), modulates IR-IRS1-PI3K-AKT signaling via regulating the phosphorylation of IR. | 23896986 |
| 2016-04-23 11:32:00 | IRTKS functions as a negative modulator of excessive inflammation in viral infections. | 26348439 |
| Type | IDs |
|---|---|
| Synonymous | 1300006M19Rik, AI585895, IRTKS |
| Gene |
UniProtKB-ID:
BI2L1_MOUSE
UniprotKB:
Q9DBJ3
UniParc:
UPI0000028331
EMBL:
BC015459,
AK004918
Ensembl:
ENSMUSG00000038859
KO:
mmu:66898
|
| Nucleutide sequences |
EMBL-CDS:
AAH15459.1,
BAB23669.1
Ensembl_TRS:
ENSMUST00000055190
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000053129
RefSeq:
NP_080109.1
|
| Others |
UniRef100:
UniRef100_Q9DBJ3
UniRef90:
UniRef90_Q9DBJ3
UniRef50:
UniRef50_Q9DBJ3
UniGene:
Mm.18814
CCDS:
CCDS39378.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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