| Type | Description |
|---|---|
| Definition | WW domain containing E3 ubiquitin protein ligase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 12:27:00 | Knockdown of WWP2 suppresses gastric cancer tumor growth in vivo. WWP2 promotes proliferation of gastric cancer cells by downregulating PTEN, which may provide new therapeutic targets for gastric cancer. | 31677789 |
| 2019-08-24 12:19:00 | Study delineatea a novel regulatory pathway that involves Sox9-[Wwp1/Wwp2/miR-140]-Fyn required for axon specification, acquisition of pyramidal morphology, and proper laminar distribution of cortical neurons. | 30392800 |
| 2019-06-29 11:18:00 | Wwp2 has a role in protecting cartilage from osteoarthritis by suppressing Runx2-induced Adamts5 via Runx2 poly-ubiquitination and degradation. | 31160553 |
| 2019-04-20 11:38:00 | Itch and WWP2 cooperate to regulate TH2 differentiation by enhancing the strength of the TCR signal via inducing atypical ubiquitination of the phosphatase SHP-1. | 29925997 |
| 2019-04-13 10:05:00 | Letter: conclude that expression of miR-140, and not Wwp2 protein is required for proper craniofacial development. | 29695789 |
| Type | IDs |
|---|---|
| Synonymous | 1300010O06Rik, AA690238, AIP2, AW554328 |
| Gene |
UniProtKB-ID:
WWP2_MOUSE,
I3RSH5_MOUSE,
Q3TXI7_MOUSE
UniprotKB:
Q9DBH0,
I3RSH5,
Q3TXI7
UniParc:
UPI00005AD2A3,
UPI0000006C19
EMBL:
AK004962,
AK090392,
HQ896246,
BC039921,
JN712751,
AC132126,
AK159248,
AK088936,
BC004712,
BC048184
Ensembl:
ENSMUSG00000031930
KO:
mmu:66894
|
| Nucleutide sequences |
EMBL-CDS:
BAB23702.1,
AAH48184.1,
AAH04712.1,
BAC41195.1,
AAH39921.1,
BAC40661.1,
AFK29260.1,
ADZ74077.1,
BAE34929.1
Ensembl_TRS:
ENSMUST00000166615,
ENSMUST00000212543
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000132224,
ENSMUSP00000148813
RefSeq:
NP_080106.1,
XP_006531362.1,
XP_006531364.1
|
| Others |
UniRef100:
UniRef100_Q9DBH0
UniRef90:
UniRef90_O00308
UniRef50:
UniRef50_O00308
UniGene:
Mm.390058
CCDS:
CCDS40467.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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