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668929 Rad21l

668929

Rad21l

RAD21-like (S. pombe)

protein-coding

Mus musculus

基因描述

Type Description
Definition RAD21-like (S. pombe)

研究结论

Date Results Publications
2018-05-19 11:15:00 when ectopically expressed in somatic cells, can promote homologous chromosome adjacency, which resembles the homolog pairing normally seen during meiosis 28239026
2017-11-18 10:42:00 Our genetic analysis demonstrates that cohesins containing STAG3 and REC8 are the main complex required for centromeric cohesion, and RAD21L cohesins are required for normal clustering of pericentromeric heterochromatin. Furthermore, the STAG3/REC8 and STAG3/RAD21L cohesins are the primary cohesins required for axis formation. 27172213
2017-06-10 11:54:00 These results strongly support the previous proposition that RAD21L is an atypical cohesin that establishes the association between homologs rather than sister chromatids. 27665783
2017-04-29 10:06:00 super resolution microscopy revealed synapsis-associated SYCP1 aberrantly deposited between sister chromatids and on single chromatids in Smc1b-/-Rad21L-/- cells. 27792785
2014-05-03 10:47:00 Disruption of meiosis-specific cohesin RAD21L precludes the initial association of homologs as well as the subsequent pairing in spermatocytes 24589552

名称对应

Type IDs
Synonymous Gm14160, MeiRAD21L, Rad21l1
Gene
UniProtKB-ID: RD21L_MOUSE
UniprotKB: A2AU37
UniParc: UPI0001F302A8
EMBL: AB574185, HQ603828, AL928988, AB602048
Ensembl: ENSMUSG00000074704
KO: mmu:668929
Nucleutide sequences
EMBL-CDS: BAJ49869.1, BAJ53091.1, CAM23443.1, AEF15807.1
Ensembl_TRS: ENSMUST00000180195
Protein sequencees
Ensembl_PRO: ENSMUSP00000136918
RefSeq: NP_001263329.1, XP_006500107.1, XP_006500106.1, XP_006500105.1
Others
UniRef100: UniRef100_A2AU37
UniRef90: UniRef90_A2AU37
UniRef50: UniRef50_A2AU37
UniGene: Mm.473683
CCDS: CCDS50747.2

全选

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