Mfsd1 - major facilitator superfamily domain containing 1-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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66868 Mfsd1

基因描述

Type	Description
Definition	major facilitator superfamily domain containing 1

研究结论

Date	Results	Publications
2020-03-14 11:33:00	Mfsd1 knockout mice develop splenomegaly and severe liver disease. Proteomics of isolated lysosomes from Mfsd1 knockout mice revealed GLMP as a critical accessory subunit for MFSD1. MFSD1 and GLMP physically interact. GLMP is essential for the maintenance of normal levels of MFSD1 in lysosomes and vice versa.	31661432
2017-07-01 11:35:00	Protein expression of MFSD1 is in mouse brain regions is specifically affected by altered nutrient uptake.	27981419

名称对应

Type	IDs
Synonymous	1200003O06Rik
Gene	UniProtKB-ID: MFSD1_MOUSE UniprotKB: Q9DC37 UniParc: UPI0000022CBD EMBL: AK159554, AK135235, AK136108, AK075859, AK152444, AK004586, BC024891 Ensembl: ENSMUSG00000027775 KO: mmu:66868
Nucleutide sequences	EMBL-CDS: BAE22467.1, AAH24891.1, BAE22824.1, BAE31224.1, BAE35179.1, BAC36010.1, BAB23391.1 Ensembl_TRS: ENSMUST00000029344
Protein sequencees	Ensembl_PRO: ENSMUSP00000029344 RefSeq: NP_080089.1
Others	UniRef100: UniRef100_Q9DC37 UniRef90: UniRef90_Q9DC37 UniRef50: UniRef50_Q9DC37 UniGene: Mm.491153 CCDS: CCDS38450.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
32959924	Characterization of the complex of the lysosomal membrane transporter MFSD1 and its accessory subunit GLMP. FASEB J David Massa LÃ³pez , Lea KÃ¤hlau , Katharina Esther Julia Jungnickel , Christian LÃ¶w , Markus Damme	2020-11-01	-
31661432	The lysosomal transporter MFSD1 is essential for liver homeostasis and critically depends on its accessory subunit GLMP. Elife David Massa LÃ³pez , Melanie Thelen , Felix Stahl , Christian Thiel , Arne Linhorst , Marc Sylvester , Irm Hermanns-Borgmeyer , Renate LÃ¼llmann-Rauch , Winnie Eskild , Paul Saftig , Markus Damme	2019-10-29	-
27981419	The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake. J. Mol. Neurosci. Emelie Perland , Sofie V Hellsten , Emilia Lekholm , Mikaela M Eriksson , Vasiliki Arapi , Robert Fredriksson	2017-02-01	-
21677750	A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley	2011-06-15	-
18287559	GUDMAP: the genitourinary developmental molecular anatomy project. J Am Soc Nephrol Andrew P McMahon , Bruce J Aronow , Duncan R Davidson , Jamie A Davies , Kevin W Gaido , Sean Grimmond , James L Lessard , Melissa H Little , S Steven Potter , Elizabeth L Wilder , Pumin Zhang , GUDMAP project	2008-04-01	-
18554416	Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. Brad G Hoffman , Bogard Zavaglia , Joy Witzsche , Teresa Ruiz de Algara , Mike Beach , Pamela A Hoodless , Steven J M Jones , Marco A Marra , Cheryl D Helgason	2008-01-01	Fam174b, Ugt2b34, Emilin1, Akap9, Hepacam2, Cyp4v3, Lars2, Gck, Acly, Ces1d, Mycbpap, Fam110c, Card10, Arap3, Fam111a, Ssr1, Ankrd1, Ltbp4, Cald1, Ctrl, Cpa1, Clps, Vimp, Cela1, Fgb, Rap1gap, Acadl, Ace, Acp5, Chrna1, Tle6, Actc1, Actn2, Acta2, Adamts1, Adcy7, Plin2, Afp, Alcam, Ambp, Mat1a, Amy1, Anxa3, Anxa4, Ap1g2, Aplp1, Apoa1, Apoa2, Aqp1, Arc, Arg1, Arx, Ass1, Neurod4, Neurog3, Atp2a2, Bcap29, Bex2, Bgn, Klf5, Btg2, Btk, Serping1, Calca, Calm1, Calm2, Casp3, Serpina6, Cck, Cckar, Cd2ap, Cd34, Cd44, Cdk11b, Cdh1, Cdkn1a, Cdkn1c, Cel, Cfh, Chga, Chgb, Cited1, Cldn3, Clu, Cnih1, Plk3, Col14a1, Col15a1, Col3a1, Col5a2, Col6a1, Col9a2, Col1a1, Col1a2, Coq7, Cox6a2, Crabp2, Cryba2, Dnajc5
16141073	Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G EngstrÃ¶m , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium	2005-09-02	Gm14018, Gm14964, F630206G17Rik, Oog3, Notumos, Ldlrap1, Mdn1, Pydc3, 9330171B17Rik, Mfap1b, Tmsb15b2, Gm12802, E430020m11rik, Gm11335, Gm15772, Gm17762, A930017K11Rik, LOC100036513, Gata5os, Umad1, Gm16982, Gm9887, Gm9872, LOC100036530, Gm9934, Gm9913, Gm11149, BC028777, Gm13999, LOC100036540, Gm9744, Gm9983, D630002J18Rik, Gm16525, Gm11696, Dnajc3, 9430060I03Rik, Gm12359, 4921516A02Rik, Fam129c, Gm10589, Rsph3b, Rnaset2a, 5430403G19Rik, D030047H15Rik, Gm13274, B930046K06Rik, Gm10862, Gm10792, Gm10802, Gm10532, G730003C15Rik, Runx2os1, Gm15612, Gm10856, Gm10857, Gm10685, Gm10803, Gm10723, F630028O10Rik, Gm10836, Gm10405, Gm10513, Gm10609, F630201L12Rik, 4932427H20Rik, Zfp389, Gm10763, Gm10062, Gm10714, Gm10531, Gm10876, Gm10750, Gm10433, Gm10837, Gm10647, Gm10648, Gm10650, Gm10610, F830115B05Rik, Gm10473, Gm10614, Gm10286, G730046D07Rik, Gm10287, Gm10785, Gm10183, Gm10512, 1700061E17Rik, Gm44113, Gm10579, Gm10741, Gm10827, Gm10522, Gm10536, Gm15998, Faddos, D130050E23Rik, Gm10735
16141072	The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C SchÃ¶nbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)	2005-09-02	-
15782199	Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Nat. Methods Akira Watahiki , Kazunori Waki , Norihito Hayatsu , Toshiyuki Shiraki , Shinji Kondo , Mari Nakamura , Daisuke Sasaki , Takahiro Arakawa , Jun Kawai , Matthias Harbers , Yoshihide Hayashizaki , Piero Carninci	2004-12-01	Ldlrap1, Mfap1b, Dnajc3, Fam129c, Rsph3b, Rnaset2a, Fam174b, Gm9797, Gm2296, Gm15429, Atp6v0c-ps2, Kcnj13, Gm10291, Gm15264, Rpl3-ps1, Gm4482, Srcap, Tpt1-ps3, Rps2-ps6, Orai2-ps, Tdrd7, Sco2, Pafah2, Akna, H6pd, Stx12, Gm15590, Osbpl9, AU040320, Ppp1r8, Bsdc1, Gm37013, Slc44a1, Zfand2a, Rpl5, LOC100503956, Atg14, Rell1, Slc15a4, Noc4l, Psph, 9330133O14Rik, Mapre3, Usp30, Ube3c, Rita1, Tbc1d14, Gm21685, Chpf2, Tyw1, Rab28, Zfp513, LOC101055802, Zfp282, Snx21, Rpusd3, Itfg2, Pot1a, Tada3, Brk1, Eogt, Dhx32, Ric8a, Inpp5f, Plekhg2, Hsd3b7, Mob2, Prkd2, Vrk3, Grwd1, Pwwp2b, Spty2d1, Faap24, Ints4, Rrp8, Unc45a, Sf3b3, D8Ertd738e, Usb1, Smim19, Dohh, Fam192a, Enkd1, Prmt9, Zdhhc7, Snapc2, Gpat4, Ankrd10, Cog4, Clk3, Xylb, Imp3, Cmtm7, Ano10, Alg9, Plekho2, Mapkapk3, Acad11, Gm30491
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team	2004-10-01	Ldlrap1, Dnajc3, Rnaset2a, Btnl1, Isg15, Cyp3a41b, Ly6c2, Ccl21b, Eif3j2, Mup18, Lrrc19, Rcc1, 1700047I17Rik2, Pcsk9, Adat3, Tdrd7, Sco2, Gpr153, Pafah2, Gm44504, H6pd, Adprhl2, Gpn2, Rusc2, Stx12, Ppp1r8, Smpdl3b, Fam46b, Bsdc1, Slc44a1, Zfand2a, Rubcn, Kifc1, Pifo, C030017K20Rik, Cbarp, Rpl5, Micalcl, Atg14, Lrrc8c, Noc4l, Nsun5, Psph, Trrap, Mapre3, Ube3c, Tbc1d14, Hscb, Tyw1, Emilin1, Rab28, Pot1a, Parp11, Tada3, Tra2a, Brk1, Fbxl14, Phrf1, Plekha1, Gm21975, Ric8a, Mob2, Prkd2, Ccp110, Vrk3, Grwd1, Nlrp6, Trim68, Psip1, Spred3, Faap24, Ints4, Rrp8, Unc45a, Igflr1, Sf3b3, D8Ertd738e, Usb1, Champ1, Smim19, Exoc8, Gadd45gip1, Phkb, Dohh, Fam192a, Enkd1, Taf5l, Zdhhc7, Snapc2, Ak6, Gpat4, Dcun1d2, Ankrd10, Cog4, Hinfp, Lars2, Xylb, Imp3, Cmtm7

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