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66853 Pnpla2

66853

Pnpla2

patatin-like phospholipase domain containing 2

protein-coding

Mus musculus

基因描述

Type Description
Definition patatin-like phospholipase domain containing 2

研究结论

Date Results Publications
2020-09-26 13:03:00 Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy. 31185001
2020-08-13 13:48:00 In summary, our data reveal new cellular and physiological mechanisms underlying the beneficial effects of 5-PAHSA and its relation to insulin action in adipocytes and independently confirm a PAHSA metabolite reservoir linked to ATGL-mediated lipolysis. 31806624
2020-05-09 13:19:00 The role of ATGL and its deficiency in lipid and glucose homeostasis in humans and transgenic mice has been discussed. (Review) 31757217
2018-07-14 11:54:00 ATGL in brown adipose tissue is not a prerequisite for cold-induced thermogenesis in vivo. 28988821
2018-06-23 10:35:00 Non-cardiac ATGL-mediated modulation of the cardiac lipidome may play an important role in the pathogenesis of chronic heart failure. 29320510

名称对应

Type IDs
Synonymous 0610039C21Rik, 1110001C14Rik, Atgl, TTS-2.2
Gene
UniProtKB-ID: PLPL2_MOUSE
UniprotKB: Q8BJ56
UniParc: UPI00004871A0, UPI00000EB738, UPI0000025B95
EMBL: AK150184, AK002826, BC019188, BC044781, AK031609, AY731699, U89431, AY894805, BC064747, AY510273, AK003207
Ensembl: ENSMUSG00000025509
KO: mmu:66853
Nucleutide sequences
EMBL-CDS: BAB22387.1, AAH44781.1, AAC36536.1, AAS48458.1, BAB22643.1, AAH64747.1, BAE29364.1, AAW81963.1, AAU33824.1, AAH19188.1, BAC27476.1
Ensembl_TRS: ENSMUST00000064151, ENSMUST00000164016
Protein sequencees
Ensembl_PRO: ENSMUSP00000065116, ENSMUSP00000127149
RefSeq: NP_001157161.1, NP_080078.2
Others
UniRef100: UniRef100_Q8BJ56
UniRef90: UniRef90_Q8BJ56
UniRef50: UniRef50_Q8BJ56
UniGene: Mm.29998
CCDS: CCDS22015.1, CCDS52445.1

全选

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