| Type | Description |
|---|---|
| Definition | tafazzin |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:02:00 | Tafazzin deficiency impairs CoA-dependent oxidative metabolism in cardiac mitochondria. | 32665401 |
| 2020-03-14 11:22:00 | AAV-Mediated TAZ Gene Replacement Restores Mitochondrial and Cardioskeletal Function in Barth Syndrome. | 30070157 |
| 2019-12-14 11:34:00 | Tafazzin-deficient mice hearts display reduced HIF-1alpha levels and undergo maladaptive hypertrophy with heart failure in response to pressure overload challenge. | 30332638 |
| 2019-09-28 10:42:00 | in vitro studies demonstrate that mitochondria-targeted antioxidants improve contractile capacity in TAZ-deficient cardiomyocytes. The purpose of the present study was to determine if resolving mitochondrial oxidative stress would be sufficient to prevent cardiomyopathy and skeletal myopathy in vivo using a mouse model of Barth Syndrome | 30008435 |
| 2019-09-21 11:27:00 | Tafazzin was elevated in the hearts of high-fat-diet fed mice.Increased tafazzin contributes to insulin resistance via mediating Drp-1 translocation to the mitochondria. | 30632304 |
| Type | IDs |
|---|---|
| Synonymous | 5031411C02Rik, 9130012G04Rik, AW107266, AW552613, G4.5 |
| Gene |
UniProtKB-ID:
I7HJS2_MOUSE,
Q91WF0_MOUSE,
Q810E8_MOUSE,
H3BK99_MOUSE
UniprotKB:
I7HJS2,
Q91WF0,
Q810E8,
H3BK99
UniParc:
UPI000002116E,
UPI0002467544,
UPI0000183C6C,
UPI0000EE0615
EMBL:
AY231459,
AK075615,
AK160327,
AL807376,
AY231460,
BC015305
Ensembl:
ENSMUSG00000009995
KO:
mmu:66826
|
| Nucleutide sequences |
EMBL-CDS:
CAM24341.1,
CAM24340.1,
BAC35860.1,
AAO84333.1,
AAH15305.1,
BAE35740.1,
AAO84334.1
Gene_ORFName:
RP23-436K3.6-015,
RP23-436K3.6-001
Ensembl_TRS:
ENSMUST00000114180,
ENSMUST00000069722,
ENSMUST00000124200,
ENSMUST00000132437
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109818,
ENSMUSP00000065270,
ENSMUSP00000134745,
ENSMUSP00000135308
RefSeq:
XP_006528307.1,
NP_001229544.1,
NP_852657.1,
NP_001167018.1,
XP_030107342.1,
XP_006528311.1,
XP_006528309.1,
XP_036017969.1,
XP_030107343.1,
XP_011245966.1,
NP_001229545.1,
XP_006528310.1,
XP_030107341.1,
XP_006528313.1,
XP_011245964.1,
XP_036017971.1,
NP_001277667.1,
XP_006528312.1,
XP_036017970.1
|
| Others |
UniRef100:
UniRef100_I7HJS2,
UniRef100_Q810E8,
UniRef100_H3BK99,
UniRef100_Q91WF0
UniRef90:
UniRef90_H3BK99,
UniRef90_Q6IV77,
UniRef90_Q810E8
UniRef50:
UniRef50_Q6IV77,
UniRef50_Q4KLG6,
UniRef50_H3BK99
UniGene:
Mm.268483
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员