| Type | Description |
|---|---|
| Definition | PYD and CARD domain containing |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:40:00 | beta-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia. | 32187546 |
| 2021-03-13 13:24:00 | ASC regulates platelet activation and contributes to thrombus formation independent of NLRP3 inflammasome. | 32782151 |
| 2021-02-27 13:54:00 | Selective inhibition of NLRP3 inflammasome by designed peptide originating from ASC. | 32648626 |
| 2021-01-23 12:59:00 | ASC Modulates CTL Cytotoxicity and Transplant Outcome Independent of the Inflammasome. | 32444423 |
| 2020-10-24 14:12:00 | Short-chain fatty acids bind to apoptosis-associated speck-like protein to activate inflammasome complex to prevent Salmonella infection. | 32991574 |
| Type | IDs |
|---|---|
| Synonymous | 9130417A21Rik, Asc, CARD5, TMS-1, TNS1, masc |
| Gene |
UniProtKB-ID:
ASC_MOUSE,
Q54AA2_MOUSE
UniprotKB:
Q9EPB4,
Q54AA2
UniParc:
UPI000000131E
EMBL:
AB059327,
AK009852,
AK018682,
AF310104,
AB032249,
AK007742,
AK152677,
BC008252
Ensembl:
ENSMUSG00000030793
KO:
mmu:66824
|
| Nucleutide sequences |
EMBL-CDS:
AAH08252.1,
AAG30287.1,
BAB25229.1,
BAB16609.1,
BAB31341.1,
BAB26543.1,
BAE31409.1,
BAB97214.1
Ensembl_TRS:
ENSMUST00000033056
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000033056
RefSeq:
NP_075747.3
|
| Others |
UniRef100:
UniRef100_Q9EPB4
UniRef90:
UniRef90_Q9EPB4
UniRef50:
UniRef50_Q9EPB4
UniGene:
Mm.24163
CCDS:
CCDS21888.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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