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66822 Fbxo25

66822

Fbxo25

F-box protein 25

protein-coding

Mus musculus

基因描述

Type Description
Definition F-box protein 25

研究结论

Date Results Publications
2015-08-29 10:28:00 our findings reveal a novel mechanism for regulation of SCFFbox25-dependent Nkx2-5 and Tbx5 ubiquitination in cardiac development and provide a new insight into the regulatory mechanism of Nkx2-5 and Tbx5 transcriptional activity. 25725482
2011-09-10 12:10:00 Altogether, Fbxo25 acts as an ubiquitin E3 ligase to target cardiac transcription factors including Nkx2-5, Isl1, and Hand1, indicating that cardiac protein homeostasis through Fbxo25 has a pivotal impact on cardiac development. 21596019
2010-01-21 00:00:00 mFbx25 shows predominantly neuronal expression and in adult mouse brain, expression is confined to the hippocampus, the cerebral cortex and the Purkinje cell layer 16278047
2010-01-21 00:00:00 The cellular distribution of FBXO25 and its colocalization with some nuclear proteins is investigated by using immunochemical and biochemical approaches. 18287534
2010-01-21 00:00:00 FBXO25 is a novel F-box protein analogous to atrogin-1, which is not involved in muscle atrophy. 16714087

名称对应

Type IDs
Synonymous 9130015I06Rik, AI649137, Fbx25
Gene
UniProtKB-ID: FBX25_MOUSE, A0A1B0GRC8_MOUSE, Q3UYF5_MOUSE
UniprotKB: Q9D2Y6, A0A1B0GRC8, Q3UYF5
UniParc: UPI00005ABAE7, UPI0000029D2F, UPI0000D8AD38
EMBL: AK134722, BC014749, AC139186, AK008027, AK018626
Ensembl: ENSMUSG00000038365
KO: mmu:66822
Nucleutide sequences
EMBL-CDS: AAH14749.1, BAB31315.1, BAB25418.1, BAE22257.1
Ensembl_TRS: ENSMUST00000043520, ENSMUST00000209913
Protein sequencees
Ensembl_PRO: ENSMUSP00000039544, ENSMUSP00000147467
RefSeq: XP_030099589.1, NP_080061.1, NP_001345990.1, NP_001334245.1
Others
UniRef100: UniRef100_Q3UYF5, UniRef100_A0A1B0GRC8, UniRef100_Q9D2Y6
UniRef90: UniRef90_Q9D2Y6
UniRef50: UniRef50_Q969P5
UniGene: Mm.37950
CCDS: CCDS22118.1

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