例如:"NBL1", "4681", "drought"
收藏
66821 Bcs1l

66821

Bcs1l

BCS1-like (yeast)

protein-coding

Mus musculus

基因描述

Type Description
Definition BCS1-like (yeast)

研究结论

Date Results Publications
2020-04-25 10:49:00 This study reports structures of mouse BCS1L in two different conformations, representing three nucleotide states. The apo and ADP-bound structures reveal a homo-heptamer and show a large putative substrate-binding cavity accessible to the matrix space. ATP binding drives a contraction of the cavity by concerted motion of the ATPase domains, which could push substrate across the membrane. 32042153
2017-07-01 11:18:00 COX7A2L/SCAFI and Pre-Complex III Modify Respiratory Chain Supercomplex Formation in Different Mouse Strains with a Bcs1l Mutation. 27997587
2015-03-24 15:04:00 Studies in the yeast BCS1 ortholog indicate that the Bcs1 protein is anchored in the mitochondrial inner membrane, despite the absence of an N-terminal targeting sequence. Targeting occurs via charged amino acids near the transmembrane domain that act as an internal targeting signal. 8599931
2012-12-08 10:59:00 Metabolite profiles reveal energy failure and impaired beta-oxidation in liver of mice with complex III deficiency due to a BCS1L mutation. 22829922
2011-03-19 10:37:00 The GRACILE mutation introduced into Bcs1l causes postnatal complex III deficiency and is a viable mouse model for mitochondrial hepatopathy. 21274865

名称对应

Type IDs
Synonymous 9130022O19Rik
Gene
UniProtKB-ID: BCS1_MOUSE
UniprotKB: Q9CZP5
UniParc: UPI000002280A
EMBL: AK012324, AK079385, AK078925, BC019781
Ensembl: ENSMUSG00000026172
KO: mmu:66821
Nucleutide sequences
EMBL-CDS: BAC37464.1, BAB28162.1, AAH19781.1, BAC37629.1
Ensembl_TRS: ENSMUST00000027358, ENSMUST00000113732, ENSMUST00000113733
Protein sequencees
Ensembl_PRO: ENSMUSP00000109362, ENSMUSP00000027358, ENSMUSP00000109361
RefSeq: NP_001292581.1, NP_080060.1
Others
UniRef100: UniRef100_Q9CZP5
UniRef90: UniRef90_Q9Y276
UniRef50: UniRef50_Q9Y276
UniGene: Mm.358700
CCDS: CCDS15051.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员