| Type | Description |
|---|---|
| Definition | ubiquitin-conjugating enzyme E2W (putative) |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 11:46:00 | Expression levels of UBE2W in mouse testes were gradually elevated from 2 to 10 weeks, while were significantly deceased in the testes with hypospermatogenesis. When UBE2W expression was successfully down-regulated in spermatogenic cells, the rate of apoptosis was significantly increased and the P53/Bcl-2/caspase 6/caspase 9 signal pathways were activated. | 31710394 |
| 2018-06-30 10:25:00 | Study shows the absence of ubiquitin conjugating enzyme Ube2W in HdhQ200 knock-in mice increases levels of soluble monomeric mutant huntingtin while reducing insoluble oligomeric species. This study sheds light on the potential function of the non-canonical ubiquitin-conjugating enzyme, Ube2W, in this polyQ neurodegenerative disease. | 28986324 |
| 2016-06-28 11:45:00 | results establish that UBE2W is an important, albeit not essential, protein for early postnatal survival and normal functioning of multiple organ systems. | 26601958 |
| 2011-06-25 15:02:00 | UBE2W regulates FANCD2 monoubiquitination by mechanisms different from UBE2T and HRR6. | 21229326 |
| Type | IDs |
|---|---|
| Synonymous | 6130401J04Rik |
| Gene |
UniProtKB-ID:
UBE2W_MOUSE,
Q3V321_MOUSE
UniprotKB:
Q8VDW4,
Q3V321
UniParc:
UPI00005AB703,
UPI0000028CC2
EMBL:
AK044463,
AK082233,
AC157362,
AC162448,
AK046086,
AK050679,
AK050923,
AK077997,
AK015348,
BC020124
Ensembl:
ENSMUSG00000025939
KO:
mmu:66799
|
| Nucleutide sequences |
EMBL-CDS:
BAC32599.1,
BAB29807.1,
BAC38443.1,
BAC31935.1,
BAC34377.1,
AAH20124.1,
BAC37094.1,
BAE43345.1
Ensembl_TRS:
ENSMUST00000117146,
ENSMUST00000182554
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000112741,
ENSMUSP00000138110
RefSeq:
XP_006495620.1,
NP_001257946.2,
XP_011236704.1,
NP_001257945.2,
NP_080049.3
|
| Others |
UniRef100:
UniRef100_Q3V321,
UniRef100_Q8VDW4
UniRef90:
UniRef90_Q3V321,
UniRef90_Q8VDW4
UniRef50:
UniRef50_Q8VDW4,
UniRef50_A0A5F9D099
UniGene:
Mm.122430
CCDS:
CCDS48224.3
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员