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6671 SP4

6671

SP4

Sp4 transcription factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition Sp4 transcription factor

研究结论

Date Results Publications
2017-12-09 11:39:00 Sp1, Sp3 and Sp4 are non-oncogene addiction (NOA) genes and are attractive drug targets for individual and combined cancer chemotherapies. 26967243
2017-09-09 14:41:00 Common risk factors in the SP4 gene are associated with schizophrenia, although not with MDD, in the Han Chinese population. 26450579
2017-06-03 10:09:00 IN TMD patients, a novel locus at genome-wide level of significance (rs73460075, OR = 0.56, P = 3.8 x 10(-8)) in the intron of the dystrophin gene DMD (X chromosome), and a suggestive locus on chromosome 7 (rs73271865, P = 2.9 x 10(-7)) upstream of the Sp4 ( SP4) gene were identified in the discovery cohort, but neither of these was replicated. 28081371
2016-07-16 11:29:00 Results indicate that SP4 S770 phosphorylation is increased in the cerebellum in bipolar disorder that committed suicide and in severe schizophrenia, and may be part of a degradation signal that controls Sp4 abundance in cerebellar granule neurons 26049820
2016-02-06 11:46:00 O-GlcNAc modification of Sp3 and Sp4, but not Sp2 transcription factors negatively regulates their transcriptional activities. 26431879

名称对应

Type IDs
Synonymous HF1B, SPR-1
Gene
UniProtKB-ID: SP4_HUMAN, Q32M51_HUMAN, A0A3B3IRW4_HUMAN
UniprotKB: Q02446, Q32M51, A0A3B3IRW4
UniParc: UPI00005DC76B, UPI000013C807, UPI0000529D53
EMBL: AK289728, AC004595, BC109301, X68561, BC109300, CH471073, KF458401
Ensembl: ENSG00000105866
KO: hsa:6671
Nucleutide sequences
EMBL-CDS: AAI09301.1, EAW93733.1, BAF82417.1, CAA48563.1, AAI09302.1
Ensembl_TRS: ENST00000222584, ENST00000649633
Protein sequencees
Ensembl_PRO: ENSP00000222584, ENSP00000496957
RefSeq: NP_001313471.1, NP_003103.2, XP_011513789.1, XP_005249886.1, XP_016868046.1, XP_011513788.1, NP_001313472.1
Others
UniRef100: UniRef100_Q02446, UniRef100_Q32M51, UniRef100_A0A3B3IRW4
UniRef90: UniRef90_Q02446, UniRef90_A0A2R8MYI0, UniRef90_A0A4W2EYQ2
UniRef50: UniRef50_Q62445, UniRef50_Q02446
UniGene: Hs.88013
CCDS: CCDS5373.1

全选

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