| Type | Description |
|---|---|
| Definition | TBC1 domain family, member 15 |
| Date | Results | Publications |
|---|---|---|
| 2017-11-26 01:13:00 | nigericin-induced mitochondria fission was rescued by knockdown of either dynamin-related protein 1 or TBC1 domain family member 15 (TBC1D15), which are two distinct mitochondria fission regulators, only TBC1D15 restored the activity of the STING pathway, which indicates that inflammasome-activating signals curtail STING pathway activation via TBC1D15. | 28729291 |
| 2013-09-14 12:12:00 | identify TBC1D15 as a Numb-associated protein and demonstrate that its amino-terminal domain disengages p53 from Numb, triggering p53 proteolysis and promoting self-renewal and pluripotency | 23468968 |
| 2010-06-28 11:58:00 | although only TBC1D15/Rab7-GAP altered Rab7-GTP levels, both Rab7-GAP and mVps39 regulate lysosomal morphology and play a role in maintaining growth factor dependence | 20363736 |
| 2010-01-21 00:00:00 | TBC1D15 may be involved in Rab7-mediated late endosomal trafficking | 16055087 |
| Type | IDs |
|---|---|
| Synonymous | 4432405K22Rik, AU022358, AU023730, AW557774, Ly6dl, Rab7-GAP |
| Gene |
UniProtKB-ID:
TBC15_MOUSE,
Q7TPU5_MOUSE
UniprotKB:
Q9CXF4,
Q7TPU5
UniParc:
UPI0000027339,
UPI00001A3DEA
EMBL:
AK147085,
AK078875,
BC053395,
AK014477
Ensembl:
ENSMUSG00000020130
KO:
mmu:66687
|
| Nucleutide sequences |
EMBL-CDS:
BAC37435.1,
BAB29380.1,
BAE27665.1,
AAH53395.1
Ensembl_TRS:
ENSMUST00000020339
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020339
RefSeq:
XP_006514020.1,
NP_079982.3
|
| Others |
UniRef100:
UniRef100_Q9CXF4,
UniRef100_Q7TPU5
UniRef90:
UniRef90_Q8TC07-3,
UniRef90_F7EZ89
UniRef50:
UniRef50_Q8TC07
UniGene:
Mm.22252
CCDS:
CCDS24176.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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