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6668 SP2

6668

SP2

Sp2 transcription factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition Sp2 transcription factor

研究结论

Date Results Publications
2018-02-03 11:23:00 This study presented that a Novel Mutation (Gly212Val) in the PS2 Gene Associated with Early-Onset Familial Alzheimer's Disease. 27128372
2017-09-16 11:54:00 SP2 recognized binding motifs in the human RORgammaT promoter, which was critical for maintaining expression. SP2 was necessary for maximum IL-17 expression in in vitro-differentiated Th17 cells. SP 2 plays a role in Th17-dependent physiologic and pathologic immune responses. 27256574
2016-02-06 11:46:00 O-GlcNAc modification of Sp3 and Sp4, but not Sp2 transcription factors negatively regulates their transcriptional activities. 26431879
2014-10-11 11:46:00 Sp2 is up-regulated in gastric cancer tissues 24623314
2010-03-15 12:09:00 Data show that three Sp1 motifs located between -148 and -42bp upstream of the first exon were important in basic as well as in DA-induced NSMase2 promoter activity. 19698806

名称对应

Type IDs
Gene
UniProtKB-ID: SP2_HUMAN
UniprotKB: Q02086
UniParc: UPI00005A7765, UPI0000000E02
EMBL: D28588, M97190, BC016680, CH471109, BC033814, AC018521
Ensembl: ENSG00000167182
KO: hsa:6668
Nucleutide sequences
EMBL-CDS: AAA36629.1, BAA05923.2, EAW94785.1, AAH33814.1, AAH16680.1
Ensembl_TRS: ENST00000376741
Protein sequencees
Ensembl_PRO: ENSP00000365931
RefSeq: XP_011523444.1, XP_011523441.1, XP_011523445.1, NP_003101.3, XP_006722088.1, XP_006722090.1, XP_024306660.1, XP_006722089.1, XP_011523438.1, XP_016880457.1, XP_006722086.1, XP_011523439.1, XP_011523440.1, XP_011523442.1
Others
UniRef100: UniRef100_Q02086
UniRef90: UniRef90_Q02086
UniRef50: UniRef50_Q02086
UniGene: Hs.514276
CCDS: CCDS11521.2

全选

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研究热度

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