| Type | Description |
|---|---|
| Definition | diablo, IAP-binding mitochondrial protein |
| Date | Results | Publications |
|---|---|---|
| 2014-02-01 12:19:00 | We report that an Smac-mimetic selectively induces TNF-alpha-dependent cystic renal epithelial cell death, leading to the removal of cystic epithelial cells from renal tissues and delaying cyst formation. | 23990677 |
| 2013-11-02 10:50:00 | Results demonstrate an essential and apoptosis-independent function of SMAC in tumor suppression and provide new insights into the biology and targeting of colon cancer. | 22751125 |
| 2013-06-29 11:28:00 | Identification of a novel anti-apoptotic E3 ubiquitin ligase that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC, HtrA2, and ARTS. | 23479728 |
| 2012-02-04 11:34:00 | Loss of Smac/DIABLO alters both caspase-dependent and caspase-independent intrinsic programmed cell death. | 21597464 |
| 2010-02-01 11:35:00 | Membrane-associated XIAP induces mitochondrial outer membrane permeabilization leading to cytochrome c and Smac release, which is dependent on Bax and Bak. | 19875445 |
| Type | IDs |
|---|---|
| Synonymous | 0610041G12Rik, 1700006L01Rik, AU040403, Smac |
| Gene |
UniProtKB-ID:
DBLOH_MOUSE
UniprotKB:
Q9JIQ3
UniParc:
UPI0000004110
EMBL:
AC157931,
AF203914,
AK077198,
AK012760,
AK002887,
AK133194
Ensembl:
ENSMUSG00000029433
KO:
mmu:66593
|
| Nucleutide sequences |
EMBL-CDS:
BAB28450.1,
BAC36676.1,
BAE21552.1,
AAF82190.1
Ensembl_TRS:
ENSMUST00000125652,
ENSMUST00000111587
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000115045,
ENSMUSP00000107214
RefSeq:
NP_075721.3,
XP_036021304.1
|
| Others |
UniRef100:
UniRef100_Q9JIQ3
UniRef90:
UniRef90_Q9JIQ3
UniRef50:
UniRef50_Q9NR28
UniGene:
Mm.46716
CCDS:
CCDS39270.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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