| Type | Description |
|---|---|
| Definition | DAZ interacting protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-10 10:08:00 | centrosome protein Dzip1 mediates the assembly of the BBSome-Dzip1-PCM1 complex in the centriolar satellites (CS) at the G0 phase for ciliary translocation of the BBSome. Phosphorylation of Dzip1 at Ser-210 by Plk1 (polo-like kinase 1) during the G2 phase promotes disassembly of this complex, resulting in removal of Dzip1 and the BBSome from the CS. | 27979967 |
| 2016-03-26 11:52:00 | demonstrated that Dzip1 was phosphorylated by GSK3beta at S520 in G0 phase, which increased its binding to GDI2 to promote the release of Rab8GDP at the cilium base | 25860027 |
| 2014-01-25 11:21:00 | Dzip1-dependent stabilization of Spop/HIB is evolutionarily conserved and essential for proper regulation of Gli/Ci proteins in the Hh pathway. | 24072710 |
| 2013-12-14 12:29:00 | Data indicate that the centrosomal protein DZIP1 interacts with GLI3 transcription factor in the cytoplasm and regulates Hedgehog signaling and ciliogenesis. | 23955340 |
| 2011-12-10 11:19:00 | reversible phosphorylation of Dzip1, which is controlled by the antagonistic action of CK2 and B56-containing PP2As, has an important impact on the stability of Gli transcription factors and Hh signaling. | 21878643 |
| Type | IDs |
|---|---|
| Synonymous | 2510025K24Rik, 2810422M04Rik |
| Gene |
UniProtKB-ID:
DZIP1_MOUSE
UniprotKB:
Q8BMD2
UniParc:
UPI00001E948B,
UPI00015DEE08,
UPI00003BF719
EMBL:
AK032834,
AK129256,
AK021163,
BC098211
Ensembl:
ENSMUSG00000042156
KO:
mmu:66573
|
| Nucleutide sequences |
EMBL-CDS:
AAH98211.1,
BAB32310.1,
BAC28050.1,
BAC98066.1
Ensembl_TRS:
ENSMUST00000004055,
ENSMUST00000047208
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000004055,
ENSMUSP00000039689
RefSeq:
XP_006519446.1,
XP_030103797.1,
XP_006519450.1,
NP_001347341.1,
XP_030103804.1,
XP_030103794.1,
XP_017171615.1,
XP_030103793.1,
XP_030103796.1,
XP_006519447.1,
XP_011243448.1,
XP_036014686.1,
XP_030103805.1,
NP_080219.2,
XP_030103800.1,
XP_030103801.1,
XP_036014687.1,
NP_001347342.1,
XP_006519449.1,
XP_030103799.1,
XP_030103802.1,
NP_001347340.1,
XP_006519452.1,
XP_006519454.1,
XP_030103798.1,
XP_006519451.1,
XP_030103803.1
|
| Others |
UniRef100:
UniRef100_Q8BMD2
UniRef90:
UniRef90_Q8BMD2
UniRef50:
UniRef50_Q86YF9
UniGene:
Mm.87456,
Mm.390755
CCDS:
CCDS37011.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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