| Type | Description |
|---|---|
| Definition | SOS Ras/Rho guanine nucleotide exchange factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:31:00 | miR-148a-3p inhibits NSCLC cells proliferation and epithelial-mesenchymal transition by reducing the expression of SOS2 | 30536836 |
| 2016-07-30 11:16:00 | Activating Mutations Affecting the Dbl Homology Domain of SOS2 Cause Noonan Syndrome | 26173643 |
| 2016-02-27 10:43:00 | We identified two novel genes, SOS2 and LZTR1, associated with Noonan syndrome, thereby expanding the molecular spectrum of RASopathies. | 25795793 |
| 2013-10-19 11:15:00 | multicenter pharmacogenetic study in children (ages 6-11): Data suggest that SNP in SOS2 (rs13379306) in children with growth hormone deficiency is associated with drug resistance to hormone replacement therapy with recombinant human growth hormone. | 23761422 |
| 2012-11-24 11:00:00 | intracellular Francisella tularensis novicida triggers temporal and early activation of Ras through the quaternary complex; Ras signalling by intracellular F. tularensis is essential for intracellular proliferation in the cytosol | 20618341 |
| Type | IDs |
|---|---|
| Synonymous | NS9, SOS-2 |
| Gene |
UniProtKB-ID:
SOS2_HUMAN
UniprotKB:
Q07890
UniParc:
UPI000013C6E8,
UPI000189A72C
EMBL:
CH471078,
BC117261,
L20686,
AL109758,
BC143367,
L13858
Ensembl:
ENSG00000100485
KO:
hsa:6655
|
| Nucleutide sequences |
EMBL-CDS:
AAA91852.1,
AAI43368.1,
AAI17262.1,
EAW65728.1,
EAW65727.1,
AAA35914.1
Ensembl_TRS:
ENST00000216373,
ENST00000543680
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000216373,
ENSP00000445328
RefSeq:
NP_008870.2
|
| Others |
UniRef100:
UniRef100_Q07890
UniRef90:
UniRef90_Q07890
UniRef50:
UniRef50_Q07890
UniGene:
Hs.291533
CCDS:
CCDS9697.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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