| Type | Description |
|---|---|
| Definition | angiogenic factor with G patch and FHA domains 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:10:00 | The 3' Untranslated Region Protects the Heart from Angiotensin II-Induced Cardiac Dysfunction via AGGF1 Expression. | 32061268 |
| 2019-05-11 10:24:00 | Aggf1 over-expression blocks liver fibrosis and Hepatic stellate cells (HSCs) activation. Aggf1 interacts with SMAD7 to suppress TGF signaling. DNA methylation regulates liver fibrosis and HSC activation by targeting Aggf1. | 26850475 |
| 2018-04-07 10:12:00 | AGGF1 protein therapy is effective in blocking neointimal formation after vascular injury by regulating a novel AGGF1-MEK1/2-ERK1/2-Elk-myocardin-SRF/p27 signaling pathway. | 28649088 |
| 2017-07-29 11:19:00 | Together with recent identification of somatic mutations in p110a (encoded by PIK3CA), our data establish a potential mechanistic link between AGGF1 and PIK3CA, the two genes identified for Klippel-Trenaunay syndrome (KTS) | 27522498 |
| 2017-06-24 11:36:00 | Data indicate that angiogenic factor Aggf1+/- knockout (KO) mice show reduced autophagy, which was associated with inhibition of angiogenesis and larger infarct areas. | 27513923 |
| Type | IDs |
|---|---|
| Synonymous | 2010009L17Rik, 2310029P06Rik, AW112072, Peg3, VG5Q |
| Gene |
UniProtKB-ID:
AGGF1_MOUSE,
Q3V1B3_MOUSE
UniprotKB:
Q7TN31,
Q3V1B3
UniParc:
UPI00005AB89E,
UPI000019B04B
EMBL:
AK017248,
AK009533,
AK008399,
BC052410,
AK132575,
AY500995,
AK008168,
BC027286
Ensembl:
ENSMUSG00000021681
KO:
mmu:66549
|
| Nucleutide sequences |
EMBL-CDS:
AAH52410.1,
BAB25648.3,
AAH27286.1,
BAB25506.3,
AAR97616.1,
BAE21238.1
Ensembl_TRS:
ENSMUST00000022189
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022189
RefSeq:
NP_079906.2
|
| Others |
UniRef100:
UniRef100_Q3V1B3,
UniRef100_Q7TN31
UniRef90:
UniRef90_Q7TN31
UniRef50:
UniRef50_Q8N302
UniGene:
Mm.36785
CCDS:
CCDS26697.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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