| Type | Description |
|---|---|
| Definition | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:02:00 | TAB1 regulates glycolysis and activation of macrophages in diabetic nephropathy. | 33044562 |
| 2019-12-14 10:12:00 | Study using knock-in mouse model elucidated the role of the p38alpha-TAB1 interaction during myocardial ischemia in vivo suggested that persistent p38alpha activation may be the result of the disinhibition of MAP2K3 access in the absence of TAB1 docking on p38alpha and proposed that TAB1 phosphorylation downstream of p38alpha is associated with cardiac damage during ischemia. | 30135318 |
| 2017-08-19 12:25:00 | our study uncovers that RNF114-mediated ubiquitination and degradation of TAB1 activate the NF-kappaB pathway during MZT, and thus directly link maternal clearance to early embryo development. | 28073917 |
| 2016-10-29 11:24:00 | We confirmed that PGC-1b inhibited downstream inflammatory signals via binding with TAB1 and thus preventing TAB1/TAK1 binding and TAK1 activation. | 26748475 |
| 2015-11-21 10:38:00 | The E3 ubiquitin ligase Itch inhibits p38alpha signaling and skin inflammation through the ubiquitylation of Tab1. | 25714464 |
| Type | IDs |
|---|---|
| Synonymous | 2310012M03Rik, Map3k7ip1, b2b449Clo |
| Gene |
UniProtKB-ID:
TAB1_MOUSE
UniprotKB:
Q8CF89
UniParc:
UPI00001B21E7
EMBL:
BC041110,
BC027054,
BC054369,
AB088136
Ensembl:
ENSMUSG00000022414
KO:
mmu:66513
|
| Nucleutide sequences |
EMBL-CDS:
AAH54369.1,
AAH27054.1,
BAC43729.1,
AAH41110.1
Ensembl_TRS:
ENSMUST00000023050
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023050
RefSeq:
NP_079885.2,
XP_006521322.1
|
| Others |
UniRef100:
UniRef100_Q8CF89
UniRef90:
UniRef90_Q8CF89
UniRef50:
UniRef50_Q8CF89
UniGene:
Mm.288245
CCDS:
CCDS27659.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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