Type | Description |
---|---|
Definition | late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 |
Date | Results | Publications |
---|---|---|
2020-10-10 13:02:00 | Loss of LAMTOR1 in pancreatic betacells increases glucosestimulated insulin secretion in mice. | 31939616 |
2019-04-13 12:42:00 | The amino acid-sensing pathway consisting of Lamtor1, mTORC1, and TFEB is involved in the regulation of innate immune responses. | 29686050 |
2019-03-16 12:21:00 | Here the authors report that Ube3a regulates mTORC1 signaling by targeting p18, a subunit of the Ragulator. Ube3a ubiquitinates p18, resulting in its proteasomal degradation. | 30020076 |
2018-08-25 11:59:00 | Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals. | 27731330 |
2018-08-04 11:18:00 | both the mRNA and protein levels of LAMTOR1 increase progressively in cleavage-stage mouse embryos. LAMTOR1 has a signi fi cant higher embryonic expression at 2-cell to morula stage. LAMTOR1 may play a role in the oogenesis process and probably required for further developmental stages and it may play a possible role in the process of compaction and cavitation in mice. | 29510224 |
Type | IDs |
---|---|
Synonymous | 2400001E08Rik, Pdro, p18 |
Gene |
UniProtKB-ID:
LTOR1_MOUSE
UniprotKB:
Q9CQ22
UniParc:
UPI0000023601
EMBL:
AK009320,
BC096412,
AK013389,
AK019947,
BC020142,
BC115459,
BC092062,
BC126973,
AK144476,
BC115458
Ensembl:
ENSMUSG00000030842
KO:
mmu:66508
|
Nucleutide sequences |
EMBL-CDS:
AAH96412.1,
AAH92062.1,
AAH20142.1,
BAB26214.1,
BAB31928.1,
AAI26974.1,
BAB28825.1,
BAE25909.1
Ensembl_TRS:
ENSMUST00000033131
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000033131
RefSeq:
NP_079881.2
|
Others |
UniRef100:
UniRef100_Q9CQ22
UniRef90:
UniRef90_Q6IAA8
UniRef50:
UniRef50_Q6IAA8
UniGene:
Mm.30003,
Mm.214841
CCDS:
CCDS21519.1
|
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---|---|---|---|---|---|---|---|---|
Refseq |
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