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66508 Lamtor1

66508

Lamtor1

late endosomal/lysosomal adaptor, MAPK and MTOR activator 1

protein-coding

Mus musculus

基因描述

Type Description
Definition late endosomal/lysosomal adaptor, MAPK and MTOR activator 1

研究结论

Date Results Publications
2020-10-10 13:02:00 Loss of LAMTOR1 in pancreatic betacells increases glucosestimulated insulin secretion in mice. 31939616
2019-04-13 12:42:00 The amino acid-sensing pathway consisting of Lamtor1, mTORC1, and TFEB is involved in the regulation of innate immune responses. 29686050
2019-03-16 12:21:00 Here the authors report that Ube3a regulates mTORC1 signaling by targeting p18, a subunit of the Ragulator. Ube3a ubiquitinates p18, resulting in its proteasomal degradation. 30020076
2018-08-25 11:59:00 Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals. 27731330
2018-08-04 11:18:00 both the mRNA and protein levels of LAMTOR1 increase progressively in cleavage-stage mouse embryos. LAMTOR1 has a signi fi cant higher embryonic expression at 2-cell to morula stage. LAMTOR1 may play a role in the oogenesis process and probably required for further developmental stages and it may play a possible role in the process of compaction and cavitation in mice. 29510224

名称对应

Type IDs
Synonymous 2400001E08Rik, Pdro, p18
Gene
UniProtKB-ID: LTOR1_MOUSE
UniprotKB: Q9CQ22
UniParc: UPI0000023601
EMBL: AK009320, BC096412, AK013389, AK019947, BC020142, BC115459, BC092062, BC126973, AK144476, BC115458
Ensembl: ENSMUSG00000030842
KO: mmu:66508
Nucleutide sequences
EMBL-CDS: AAH96412.1, AAH92062.1, AAH20142.1, BAB26214.1, BAB31928.1, AAI26974.1, BAB28825.1, BAE25909.1
Ensembl_TRS: ENSMUST00000033131
Protein sequencees
Ensembl_PRO: ENSMUSP00000033131
RefSeq: NP_079881.2
Others
UniRef100: UniRef100_Q9CQ22
UniRef90: UniRef90_Q6IAA8
UniRef50: UniRef50_Q6IAA8
UniGene: Mm.30003, Mm.214841
CCDS: CCDS21519.1

全选

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