| Type | Description |
|---|---|
| Definition | SKI family transcriptional corepressor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 12:32:00 | Our data show that mCORL2 and drosophila CORL share functions while mCORL1 has diverged which reinforces the current working hypothesis that neofunctionalization of a new gene can be achieved with a handful of advantageous amino acid changes in a highly conserved functional domain. | 31530634 |
| 2017-11-25 15:14:00 | The first SNP rs29972765 is located in a gene desert on chromosome 18, about 72 kb upstream of Skor2 . The second SNP rs30415957 resides in the intron of Plce1.The remaining two SNPs (rs30768258 and rs31216810) are close to each other on chromosome 19, in the vicinity of Sorbs1. Knockdown of Sorbs1 by siRNA attenuates the induction of differentiation marker gene Prl8a2 | 27449513 |
| 2014-05-10 11:38:00 | Corl2/Skor2 has a role in regulating cerebellar Purkinje cell differentiation in a pathway involving RORalpha | 24491816 |
| 2011-12-03 10:26:00 | essential function for Skor2 as a novel transcriptional regulator in Purkinje cells that acts upstream of Shh during cerebellum development | 21937600 |
| 2010-01-21 00:00:00 | Results strongly suggest that Corl2 is a specific marker for Purkinje cells in the cerebellum from their emergence until the adult stage. | 18522874 |
| Type | IDs |
|---|---|
| Synonymous | Corl2, EG664805, Fussel18, Gm7348 |
| Gene |
UniProtKB-ID:
SKOR2_MOUSE
UniprotKB:
A7M7C7
UniParc:
UPI00015BFBEB
EMBL:
AB358976
Ensembl:
ENSMUSG00000091519
KO:
mmu:664805
|
| Nucleutide sequences |
EMBL-CDS:
BAF76044.1
Ensembl_TRS:
ENSMUST00000166956
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000132338
RefSeq:
NP_001103213.1,
XP_006526499.1
|
| Others |
UniRef100:
UniRef100_A7M7C7
UniRef90:
UniRef90_A7M7C7
UniRef50:
UniRef50_A7M7C7
UniGene:
Mm.329543
CCDS:
CCDS50322.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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