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664616 MIR487B

664616

MIR487B

microRNA 487b

ncRNA

Homo sapiens

基因描述

Type Description
Definition microRNA 487b

研究结论

Date Results Publications
2021-03-20 13:26:00 miR-154-3p and miR-487-3p synergistically modulate RHOA signaling in the carcinogenesis of thyroid cancer. 31820783
2020-05-16 13:03:00 we confirmed that miR-487b is a CRC suppressor that prevents the EMT process and targets MYC, SUZ12, and KRAS to inhibit the proliferation, migration and invasion of CRC cells. Meanwhile, miR-487b is negatively regulated by DNA methylation 30791232
2019-12-07 10:24:00 miR-487b can significantly mitigate the symptoms of allergic rhinitis by inhibiting the IL-33/ST2 signaling pathway. 30556842
2019-07-06 12:55:00 In human primary cells, we confirmed the shift in miR487b targeting after editing, resulting in a edited miR487b targetome that is enriched for multiple proangiogenic pathways. miR487b is found in multiple human primary vascular cell types. The same adenosine residue is methylated in mice and human primary cells. 29284691
2018-02-24 10:35:00 The cluster 14q32.31 member miR-487b was variably under-expressed in pediatric glioma lines compared with human neural stem cells. Overexpression of miR-487b in a pediatric glioma cell line (KNS42) using lentiviral vectors led to a decrease in colony formation in soft agar (30%) (P<0.05), and decreased expression of known predicted targets PROM1 and Nestin 27739438

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Type IDs
Synonymous MIRN487B, mir-487b