| Type | Description |
|---|---|
| Definition | fission, mitochondrial 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 10:16:00 | Treatment with P110 was protective in both in vitro and in vivo models of septic cardiomyopathy, suggesting a key role of Drp1/Fis1 interaction, and a potential target to reduce its morbidity and mortality. | 30981733 |
| 2020-05-09 12:33:00 | Fis1 loss induced delayed onset muscle ultrastructure change (DOMUC) in Type I muscle and strong inflammation in response to acute exhaustive exercise (EE). | 31526891 |
| 2020-01-11 11:40:00 | a role for Drp1/Fis1-mediated excessive mitochondrial fission and dysfunction, is reported. | 30550751 |
| 2019-04-20 10:49:00 | chronically elevated IL-6 can directly induce DRP-1 and FIS-1 expression through gp130 signaling in cultured myotubes and skeletal muscle. | 30918582 |
| 2017-06-24 11:27:00 | Our data confirm that FIS1 is a key regulator in pancreatic beta cells, because both glucose-stimulated insulin secretion and mitochondrial dynamics were clearly adapted to precise expression levels of this fission protein. | 27179109 |
| Type | IDs |
|---|---|
| Synonymous | 2010003O14Rik, Ttc11 |
| Gene |
UniProtKB-ID:
FIS1_MOUSE,
D3YZ32_MOUSE,
G3X9U9_MOUSE
UniprotKB:
Q9CQ92,
D3YZ32,
G3X9U9
UniParc:
UPI0001547DD8,
UPI0000356E54,
UPI0000029954
EMBL:
AK008916,
AK004917,
AC147987,
BC010783,
AK004479,
AK008323,
AK008078
Ensembl:
ENSMUSG00000019054
KO:
mmu:66437
|
| Nucleutide sequences |
EMBL-CDS:
BAB25601.1,
BAB23324.1,
AAH10783.1,
BAB25445.1,
BAB25966.1,
BAB23668.1
Ensembl_TRS:
ENSMUST00000019198,
ENSMUST00000111097,
ENSMUST00000111094
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000019198,
ENSMUSP00000106726,
ENSMUSP00000106723
RefSeq:
NP_079838.1,
NP_001156715.1,
NP_001334433.1
|
| Others |
UniRef100:
UniRef100_G3X9U9,
UniRef100_D3YZ32,
UniRef100_Q9CQ92
UniRef90:
UniRef90_D3YZ32,
UniRef90_A5HUN3,
UniRef90_Q9CQ92
UniRef50:
UniRef50_Q9CQ92,
UniRef50_A5HUN3,
UniRef50_G5E0P0
UniGene:
Mm.25849
CCDS:
CCDS19757.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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