| Type | Description |
|---|---|
| Definition | sorting nexin 2 |
| Date | Results | Publications |
|---|---|---|
| 2014-12-06 11:14:00 | SNX2 is highly expressed in 73.3% Graves disease patients and in 93.8% thyroid nodule patients. | 23531855 |
| 2013-09-14 11:34:00 | Silencing of SNX2 markedly alters sensitivity to anticancer drugs targeted to c-Met. | 23360489 |
| 2011-03-05 11:30:00 | SNX1 and SNX2 interact with the Rac1 and RhoG guanine nucleotide exchange factor Kalirin-7. Overexpression of SNX1 or SNX2 and Kalirin-7 partially redistributes both SNXs to the plasma membrane, and results in RhoG-dependent lamellipodia formation. | 20604901 |
| 2010-01-21 00:00:00 | Data suggest that sorting nexin-2 is not essential for the regulation of endosome-to-trans Golgi network retrieval of the cation-independent mannose 6-phosphate receptor. | 16179610 |
| 2010-01-21 00:00:00 | The N-terminal domain of Abs interacts with the phox homology (PX) domain of SNX2 suggesting that PX domains may also participate in protein-protein interaction | 15690390 |
| Type | IDs |
|---|---|
| Synonymous | TRG-9 |
| Gene |
UniProtKB-ID:
SNX2_HUMAN
UniprotKB:
O60749
UniParc:
UPI0000140645,
UPI00017A6D9E
EMBL:
AF065482,
AK296596,
CH471086,
AF043453,
AC008669,
BC003382,
BT009841,
AY272044,
AK023581,
AK293671,
AC093267
Ensembl:
ENSG00000205302
KO:
hsa:6643
|
| Nucleutide sequences |
EMBL-CDS:
BAG57115.1,
BAH12394.1,
AAB99852.1,
AAH03382.1,
BAG51206.1,
AAP88843.1,
AAC17181.1,
EAW48884.1,
AAQ02693.1
Gene_ORFName:
TRG9
Ensembl_TRS:
ENST00000514949,
ENST00000379516
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000421663,
ENSP00000368831
RefSeq:
NP_003091.2,
NP_001265128.1
|
| Others |
UniRef100:
UniRef100_O60749
UniRef90:
UniRef90_O60749
UniRef50:
UniRef50_O60749
UniGene:
Hs.125352,
Hs.713554
CCDS:
CCDS64234.1,
CCDS34217.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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