| Type | Description |
|---|---|
| Definition | sorting nexin 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 12:57:00 | Sorting nexin 1 loss results in increased oxidative stress and hypertension. | 32293069 |
| 2018-05-26 11:31:00 | Data suggest that GLP1R signaling in pancreatic beta-cells leading to insulin secretion involves interactions of GLP1R with HIP1, SNX1, and SNX27; HIP1 appears to regulate coupling of cell surface GLP1R activation with endocytosis; SNX1 and SNX27 appear to control balance between GLP1R plasma membrane recycling and lysosomal degradation. | 29284659 |
| 2017-02-18 11:17:00 | SNX1 was down-regulated in CRC and associated with poor prognosis. Our data also showed that SNX1 inhibited the proliferation of CRC cells and increased the sensitivity to the most commonly used drugs for CRC. | 26643894 |
| 2016-04-23 10:51:00 | miR-95 functions as an oncogene role in non-small cell lung cancer cells by directly targeting SNX1. | 24835695 |
| 2016-03-26 12:06:00 | Results show that suppression of EGFR membrane recycling by SNX1 appears to be critical for the activation of EGFR /PI3K/AKT signaling pathway in human lung cancer cells. | 25653196 |
| Type | IDs |
|---|---|
| Synonymous | HsT17379, VPS5 |
| Gene |
UniProtKB-ID:
SNX1_HUMAN
UniprotKB:
Q13596
UniParc:
UPI000217BDBB,
UPI0000135B3E,
UPI000002B3E5
EMBL:
AF065483,
AF065484,
BT006983,
AK291752,
AC100840,
AC021541,
AK128179,
CH471082,
U53225,
BC000357
Ensembl:
ENSG00000028528
KO:
hsa:6642
|
| Nucleutide sequences |
EMBL-CDS:
BAF84441.1,
EAW77663.1,
AAP35629.1,
AAC17183.1,
BAC87312.1,
AAA98672.1,
EAW77665.1,
AAC17182.1,
AAH00357.1
Ensembl_TRS:
ENST00000261889,
ENST00000561026,
ENST00000559844
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000453567,
ENSP00000261889,
ENSP00000453785
RefSeq:
NP_001229862.1,
NP_683758.1,
NP_003090.2,
XP_005254668.1
|
| Others |
UniRef100:
UniRef100_Q13596
UniRef90:
UniRef90_Q13596
UniRef50:
UniRef50_Q13596
UniGene:
Hs.188634
CCDS:
CCDS58371.1,
CCDS32268.1,
CCDS32266.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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