| Type | Description |
|---|---|
| Definition | aprataxin |
| Date | Results | Publications |
|---|---|---|
| 2018-08-18 10:19:00 | Interaction with phosphorylated XRCC1 is a requirement for significant APTX recruitment to cellular DNA damage and enzymatic activity in cell extracts. | 29477978 |
| 2015-07-25 10:58:00 | Study demonstrates a protective role of Aptx in vivo and suggests that its loss results in progressive accumulation of DNA breaks in the nervous system, triggering hallmarks of premature ageing, systemically. | 25274775 |
| 2010-01-21 00:00:00 | neurological disorders associated with APTX mutations may be caused by the gradual accumulation of unrepaired DNA strand breaks resulting from abortive DNA ligation events | 16964241 |
| 2010-01-21 00:00:00 | aprataxin participates in chromosomal single-strand break repair | 19103743 |
| Type | IDs |
|---|---|
| Synonymous | 2410016G21Rik, AA388047, FHA-HIT |
| Gene |
UniProtKB-ID:
APTX_MOUSE
UniprotKB:
Q7TQC5
UniParc:
UPI0000003EA2,
UPI00000EB0D3,
UPI00000EA095,
UPI0000003EDB
EMBL:
AK088928,
BC021872,
AY040780,
AK005286,
AY208844,
AK010516,
AY040782,
AK077351
Ensembl:
ENSMUSG00000028411
KO:
mmu:66408
|
| Nucleutide sequences |
EMBL-CDS:
AAK91771.1,
AAP86334.1,
AAK91773.1,
BAB26998.2,
BAB23933.2,
BAC40657.1,
BAC36763.1,
AAH21872.2
Ensembl_TRS:
ENSMUST00000030119,
ENSMUST00000108103,
ENSMUST00000068125
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000124264,
ENSMUSP00000030119,
ENSMUSP00000103738
RefSeq:
XP_006538234.1,
XP_011248386.1,
XP_006538233.1,
NP_001020615.1,
XP_036020202.1,
XP_030109558.1,
NP_079821.3,
NP_001020616.1,
XP_030109559.1,
XP_006538232.1,
XP_006538230.1,
XP_006538231.1,
XP_036020204.1
|
| Others |
UniRef100:
UniRef100_Q7TQC5
UniRef90:
UniRef90_Q7TQC5
UniRef50:
UniRef50_Q7Z2E3
UniGene:
Mm.430710
CCDS:
CCDS38711.1,
CCDS38712.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员