| Type | Description |
|---|---|
| Definition | anti-silencing function 1A histone chaperone |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:23:00 | In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma. | 31744829 |
| 2018-09-08 11:54:00 | Asf1a-mediated nucleosome disassembly provides a means for resolution of bivalent domain barriers for induction of lineage-specific genes during differentiation. | 29915027 |
| 2010-03-15 12:22:00 | tousled-like kinases play important roles in DNA repair, not only by modulation of chromatin assembly via Asf1, but also by a more direct function in processing the ends of a tousled-like kinase via interaction with Rad9. | 20021694 |
| Type | IDs |
|---|---|
| Synonymous | 2310079C17Rik, C79052 |
| Gene |
UniProtKB-ID:
ASF1A_MOUSE
UniprotKB:
Q9CQE6
UniParc:
UPI0000021760
EMBL:
AK010210,
AK012376,
AK088618,
AK007804,
BC027628
Ensembl:
ENSMUSG00000019857
KO:
mmu:66403
|
| Nucleutide sequences |
EMBL-CDS:
AAH27628.1,
BAB28198.1,
BAB25269.1,
BAC40457.1,
BAB26770.1
Ensembl_TRS:
ENSMUST00000020004
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020004
RefSeq:
NP_079817.1
|
| Others |
UniRef100:
UniRef100_Q9CQE6
UniRef90:
UniRef90_Q9CQE6
UniRef50:
UniRef50_Q9CQE6
UniGene:
Mm.272989
CCDS:
CCDS23847.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
| 31744829 |
Cancer Discov Fei Li , Qingyuan Huang , Troy A Luster , Hai Hu , Hua Zhang , Wai-Lung Ng , Alireza Khodadadi-Jamayran , Wei Wang , Ting Chen , Jiehui Deng , Michela Ranieri , Zhaoyuan Fang , Val Pyon , CatrÃona M Dowling , Ece Bagdatlioglu , Christina Almonte , Kristen Labbe , Heather Silver , Alexandra R Rabin , Kandarp Jani , Aristotelis Tsirigos , Thales Papagiannakopoulos , Peter S Hammerman , Vamsidhar Velcheti , Gordon J Freeman , Jun Qi , George Miller , Kwok-Kin Wong |
2020-02-01 | - |
| 31040226 |
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Mol Cell Proteomics Joel D Federspiel , Todd M Greco , Krystal K Lum , Ileana M Cristea |
2019-08-09 | - |
| 30196744 |
ATG5 is required for B cell polarization and presentation of particulate antigens. Autophagy Florent Arbogast , Johan Arnold , Philippe Hammann , Lauriane Kuhn , Johana Chicher , Diane Murera , Justine Weishaar , Sylviane Muller , Jean-Daniel Fauny , Frédéric Gros |
2019-02-01 | - |
| 29915027 |
Proc. Natl. Acad. Sci. U.S.A. Yuan Gao , Haiyun Gan , Zhenkun Lou , Zhiguo Zhang |
2018-07-03 | - |
| 28708136 |
Differential requirements for Tousled-like kinases 1 and 2 in mammalian development. Cell Death Differ. Sandra Segura-Bayona , Philip A Knobel , Helena González-Burón , Sameh A Youssef , Aida Peña-Blanco , Ãtienne Coyaud , Teresa López-Rovira , Katrin Rein , LluÃs Palenzuela , Julien Colombelli , Stephen Forrow , Brian Raught , Anja Groth , Alain de Bruin , Travis H Stracker |
2017-11-01 | - |
| 28700664 |
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. PLoS One John P Sundberg , Soheil S Dadras , Kathleen A Silva , Victoria E Kennedy , Gaven Garland , Stephen A Murray , Beth A Sundberg , Paul N Schofield , C Herbert Pratt |
2017-01-01 | - |
| 27626380 |
High-throughput discovery of novel developmental phenotypes. Nature Mary E Dickinson , Ann M Flenniken , Xiao Ji , Lydia Teboul , Michael D Wong , Jacqueline K White , Terrence F Meehan , Wolfgang J Weninger , Henrik Westerberg , Hibret Adissu , Candice N Baker , Lynette Bower , James M Brown , L Brianna Caddle , Francesco Chiani , Dave Clary , James Cleak , Mark J Daly , James M Denegre , Brendan Doe , Mary E Dolan , Sarah M Edie , Helmut Fuchs , Valerie Gailus-Durner , Antonella Galli , Alessia Gambadoro , Juan Gallegos , Shiying Guo , Neil R Horner , Chih-Wei Hsu , Sara J Johnson , Sowmya Kalaga , Lance C Keith , Louise Lanoue , Thomas N Lawson , Monkol Lek , Manuel Mark , Susan Marschall , Jeremy Mason , Melissa L McElwee , Susan Newbigging , Lauryl M J Nutter , Kevin A Peterson , Ramiro Ramirez-Solis , Douglas J Rowland , Edward Ryder , Kaitlin E Samocha , John R Seavitt , Mohammed Selloum , Zsombor Szoke-Kovacs , Masaru Tamura , Amanda G Trainor , Ilinca Tudose , Shigeharu Wakana , Jonathan Warren , Olivia Wendling , David B West , Leeyean Wong , Atsushi Yoshiki , International Mouse Phenotyping Consortium , Jackson Laboratory , Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS) , Charles River Laboratories , MRC Harwell , Toronto Centre for Phenogenomics , Wellcome Trust Sanger Institute , RIKEN BioResource Center , Daniel G MacArthur , Glauco P Tocchini-Valentini , Xiang Gao , Paul Flicek , Allan Bradley , William C Skarnes , Monica J Justice , Helen E Parkinson , Mark Moore , Sara Wells , Robert E Braun , Karen L Svenson , Martin Hrabe de Angelis , Yann Herault , Tim Mohun , Ann-Marie Mallon , R Mark Henkelman , Steve D M Brown , David J Adams , K C Kent Lloyd , Colin McKerlie , Arthur L Beaudet , Maja BuÄan , Stephen A Murray |
2016-09-22 | - |
| 26238476 |
Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev. Biol. Jordan P Lewandowski , Fang Du , Shilu Zhang , Marian B Powell , Kristin N Falkenstein , Hongkai Ji , Steven A Vokes |
2015-10-01 |
Pkdcc,
Tecr,
Osr2,
Ap1s2,
Pmch,
Ppp2r4,
Alx4,
Apoa2,
Aprt,
Avpr2,
Prdm1,
Bmp2,
Bmp4,
Bmpr1b,
Runx3,
Cdk6,
Cntfr,
Dcn,
Dlk1,
Dlx5,
Drd3,
Ebf3,
Sparcl1,
Ednrb,
Efna1,
Eomes,
Epha3,
Foxf2,
Fzd7,
Gata5,
Gli1,
Grcc10,
Hand2,
Hccs,
Foxf1,
Hhip,
Hmga1,
Hoxa7,
Hoxb4,
Hoxc4,
Hoxd10,
Hoxd11,
Hoxd13,
Id3,
Ier2,
Ier5,
Igf1r,
Inha,
Irx3,
Isl1,
Jag1,
Kit,
Klf3,
Klf9,
Lum,
Xpnpep2,
Zfp704,
Slc8b1,
Smad7,
Meis1,
Mgmt,
Meis2,
Polr2k,
Myl4,
Nfe2l3,
Cldn11,
Pam,
Pax1,
Pax9,
Pbx1,
Enpp1,
Prkce,
Ptch1,
Ptch2,
Igdcc3,
Aldh1a2,
Mrpl23,
Sfrp2,
Shcbp1,
Slc2a1,
Ncor2,
Sox4,
Sp1,
Sall3,
Depdc7,
Pqlc2,
Tank,
Tbx2,
Tbx3,
Tbx4,
Lrrc20,
Tmem5,
Tcte3,
Stxbp6,
Tpd52l1,
Wnt11,
Cyyr1,
Xpa,
Zfp281
|
| 26365490 |
Systematic identification of factors for provirus silencing in embryonic stem cells. Cell Bin Xia Yang , Chadi A El Farran , Hong Chao Guo , Tao Yu , Hai Tong Fang , Hao Fei Wang , Sharon Schlesinger , Yu Fen Samantha Seah , Germaine Yen Lin Goh , Suat Peng Neo , Yinghui Li , Matthew C Lorincz , Vinay Tergaonkar , Tit-Meng Lim , Lingyi Chen , Jayantha Gunaratne , James J Collins , Stephen P Goff , George Q Daley , Hu Li , Frederic A Bard , Yuin-Han Loh |
2015-09-24 |
Mdn1,
Wdr92,
Rtn1,
Rcor2,
Tsr1,
Ankrd28,
Chd4,
Dnajc9,
Cops8,
Rcc2,
Chaf1b,
Aldoc,
Mta1,
Mta3,
Brca1,
Ctnna1,
Cbx1,
Cbx3,
Cbx5,
Cdh1,
Eif3a,
Smarcad1,
Wdr5,
Ppm1g,
Trip12,
Hdac2,
Hspa8,
Hsph1,
Eif3e,
Lig1,
Mcm2,
Mcm4,
Mcm6,
Mre11a,
Msh2,
Msh6,
Ppp1r12a,
Npm1,
Npm3,
Pcna,
Ppp1ca,
Prpf8,
Rad50,
Ranbp2,
Rbbp4,
Rfc1,
Reps1,
Rfc2,
Ruvbl2,
Sec23a,
Cyfip1,
Sin3a,
Smarca4,
Smarcc1,
Eftud2,
Sde2,
Gps1,
Tbl1x,
Wdr18,
Sbno2,
Kat7,
Timeless,
Tjp2,
Sec24c,
Ulk1,
Usp9x,
Uxt,
Eif3l,
Prrc2c,
Ikbkap,
Nrd1,
Ipo7,
Gatad2a,
Heatr3,
Vac14,
Rbbp7,
Esrrb,
Cops3,
Cops5,
Cops4,
Cops6,
Aifm1,
Sec23b,
Chaf1a,
Trp53bp1,
Eif3b,
Hist1h3d,
Hist1h4d,
Snrnp200,
Hdac1,
Fbxo15,
Nckap1,
Ctps,
Rif1,
Ppp6r3,
Cdc23,
Eif3g,
Ddx20,
Eif3i
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
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目前还没有研究热点人员