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66383 Iscu

66383

Iscu

iron-sulfur cluster assembly enzyme

protein-coding

Mus musculus

基因描述

Type Description
Definition iron-sulfur cluster assembly enzyme

研究结论

Date Results Publications
2016-09-10 11:03:00 ISCU expression was decreased in the majority of human liver cancer tissues, and its reduced expression was significantly associated with p53 mutation. 26560363
2015-04-25 10:25:00 IscU is a marginally stable protein at low ionic strength to the point that undergoes cold denaturation at around -8 degrees C with a corresponding dramatic decrease of enthalpy, which is consistent with the fluxional nature of the protein. 24917298
2013-07-13 13:12:00 mTORC1 associates with ISCU and phosphorylates ISCU at serine 14. This phosphorylation stabilized ISCU protein. 23508953
2011-06-18 10:56:00 Data show that complete loss of ISCU results in early embryonic death and confirm a fundamental role for ISCU in mammals. 21165651
2010-01-21 00:00:00 While IFN-gamma alone induced Nfs1 protein instability, LPS triggered a delayed decline of Nfs1, rather involving transcriptional events or mRNA instability. 17603005

名称对应

Type IDs
Synonymous 2310020H20Rik, AA407971, ISCU2, Nifu, Nifun
Gene
UniProtKB-ID: ISCU_MOUSE
UniprotKB: Q9D7P6
UniParc: UPI0000022703
EMBL: AK039834, AK083247, AK009021, BC028800, BC048409, BC096049
Ensembl: ENSMUSG00000025825
KO: mmu:66383
Nucleutide sequences
EMBL-CDS: BAC38830.1, AAH48409.1, AAH28800.1, AAH96049.1, BAC30464.1, BAB26031.1
Ensembl_TRS: ENSMUST00000026937
Protein sequencees
Ensembl_PRO: ENSMUSP00000026937
RefSeq: XP_030110615.1, XP_030110614.1, NP_079802.1, NP_001350246.1
Others
UniRef100: UniRef100_Q9D7P6
UniRef90: UniRef90_Q9H1K1
UniRef50: UniRef50_Q9H1K1
UniGene: Mm.29497
CCDS: CCDS19553.1

全选

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